摘要
目的探讨高血压患者血压变异性与肱踝脉搏波传导速度(brachial-ankle pulse wave velocity,baP-WV)的关系。方法选择原发性高血压患者313例,根据baPWV值,将其分为两组:baPWV正常组(baPWV<1 400cm/s)87例,baPWV升高组(baPWV≥1 400 cm/s)226例。比较两组患者年龄、性别构成比、血糖、血脂、血肌酐、血尿酸、血压及血压变异性。结果单因素分析显示,baPWV升高组患者的年龄、胆固醇、低密度脂蛋白、高密度脂蛋白、24 h平均收缩压、24 h收缩压变异性及24 h舒张压变异性均高于baPWV正常组(P<0.05),代入Logistic回归分析显示年龄、胆固醇、高密度脂蛋白、24 h平均收缩压、24 h收缩压变异性及24 h舒张压变异性与baPWV呈相关性(P<0.05)。结论高血压患者24 h收缩压变异性和舒张压变异性是影响baPWV的独立因素。
Objective To explore the relationship between blood pressure variability and brachial -ankle pulse wave velocity （baPWV） in hypertensive patients. Methods Totally 313 patients with essential hypertension were enrolled in this study and divided into normal baPWV group （ baPWV 〈 1 400cm/s, n = 87 ） and high baPWV group （ baPWV ≥ 1 400em/s, n= 226 ） based on their baPWV values. Age, gender ratio, fasting blood glucose （FBG） , blood lipids including cholesterol （CHO）, low- density lipoprotein cholesterol （LDL）, and high - density lipoprotein cholesterol （HDL）, serum creatinine （Cr）, blood uric acid （UA） , blood pressure, and blood pressure variability were measured. Results Univariate analysis re-vealed that age, CHO, LDL, HDL, 24 - hour systolic blood pressure, 24 - hour systolic blood pressure variability, and 24 - hour diastolic blood pressure variability were significantly higher in high baPWV group than in normal baPWV group （P 〈 0. 05 ）. Multivariate Logistic regression analysis indicated that age, CHO, HDL, 24 - hour systolic blood pressure, 24 - hour systolicblood pressure variability, and 24 - hour diastolic blood pressure variability were independent influencing factors for baPWV （P 〈 0. 05 ）. Conclusion In hypertensive patients, 24 - hour systolic blood pressure variability and 24 - hour diastolic blood pres- sure variability are independent influencing factors for baPWV.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第8期851-853,共3页
Chinese General Practice
关键词
血压变异性
肱踝脉搏波传导速度
高血压
Blood pressure variability
Brachial -ankle pulse wave velocity
Hypertension
