期刊文献+

血浆FIB、FDP及D-二聚体在妊娠期高血压疾病中的临床应用 被引量:10

The clinical application of FIB,FDP and the D-dimer in high blood pressure in pregnancy
原文传递
导出
摘要 目的:探讨妊娠期高血压患者血浆FIB、FDP及D-二聚体病理变化。方法:选择健康组非妊娠妇女80名,正常妊娠组62名,妊娠期高血压患者轻度32名、中度40名、重度28名,分别同时测量血浆FIB、FDP及D-二聚体值。结果:妊娠期高血压组血浆中FIB、FDP及D-二聚体的测定值明显高于健康非妊娠组及正常妊娠组,差异均有统计学意义(P<0.05),且随妊娠期高血压病情的严重程度而增加。结论:对于妊娠期高血压疾病临床早期预防、发现、治疗及重度妊娠期高血压疾病的DIC与子癫形成具有临床应用价值。 Objective:To study the pathological changes of FIB,FDP and the D-dimer in plasma of the patients with high blood pressure in pregnancyMethods:The 80 health no-pregnant women and 62 normal pregnancy women and 100 patients with high blood pressure in pregnancy were choose.Of the 100 patients,32 patients were mild,40 were moderate,and 28 were severe.FIB,FDP and the D-dimer value in plasma of all the women were measured respectivelyResults:FIB,FDP and the D-dimer value in plasma of the patients with high blood pressure in pregnancy were significantly higher than that of the health no-pregnant women and the normal pregnancy women(P0.05).Conclusion:Early prevention,diagnosis and treatment of hypertensive disorder complicating pregnancy have clinical application value for avoiding the occurring of DIC and edampsia
作者 娄峻 王永利
出处 《中国妇幼保健》 CAS 北大核心 2012年第11期1744-1745,共2页 Maternal and Child Health Care of China
关键词 FIB FDP D-二聚体 妊娠期高血压疾病 FIB FDP Plasma D-dimer High blood pressure in pregnancy
  • 相关文献

参考文献4

二级参考文献31

  • 1侍庆,陈晨,王学锋,王鸿利.妊娠高血压综合征患者血浆止凝血分子标志物水平变化的意义[J].中华妇产科杂志,2004,39(11):733-736. 被引量:46
  • 2陈卫中,倪宗瓒,潘晓平,刘元元,夏彦.用ROC曲线确定最佳临界点和可疑值范围[J].现代预防医学,2005,32(7):729-731. 被引量:214
  • 3Sartori M T,Serena A,Saqqiorato G,et al.Variations in fibrinolytic parameters and inhibin-A in pregnancy:related hypertensive disorders.[J] Thromb Haemost,2008,6(2):352-358.
  • 4Pwter L,Willian C.The endothelium and thrombosis[J].Semin Thromb. 2000.26(5) :463.
  • 5Hajjar KA.The endothelium in thrombosis and hemorrhage.In Thromhosis and Hemorrhage,edited by Loscalzo J,Schafter AI.Lippincott Williams Wilkins.2002.206
  • 6Robert D. Vascular-bed-specific Hemostasis and hypercoagulation states:clinical utility of activation peptide assays in predicting thrombotic events in differnent clinical population[J].Thromb Haemost, 2001,86:41.
  • 7Van MJA, De WIR. Von Willebrand factor propeptide in vascular disorder[J]. Thromb Hamost,2001,86:164.
  • 8Pelzer H,Egbring R,Seitz R,et al.Thrombin-antithrombinⅢ complex-a new parameter foe detection of thrombotic states[J].Thromb Haemost,1987,58:237
  • 9Mimuru J,Koik Y,Sumi Y,et al.Monoclonal antibodies to discrete regions in a 2-plasmin inhibitor[J].Blood,1987,69:446
  • 10Rylatt DB.An immunoassay for human D-dimer using monoclonal antibodies[J].Thromb Res,1983,31:767

共引文献18

同被引文献82

  • 1顾保罗,单才华,梁友方.纤维蛋白原D-二聚体对妊娠高血压综合征的影响[J].中国基层医药,2004,11(12):1473-1473. 被引量:9
  • 2张慧娟,费冲,邵慧珍,何其久.正常及妊高征孕妇血小板α-颗粒膜蛋白和纤溶状态的研究[J].中华妇产科杂志,1994,29(7):423-424. 被引量:42
  • 3黄尉国,王鸿利,张颖琪,朱立红,李耀辉,王学锋,程寅琳,邵慧珍,张鲁,葛维成.血浆D-二聚体检测及其临床应用[J].中华医学检验杂志,1995,18(2):71-74. 被引量:318
  • 4郦卫星,吴茅,刘建栋.常规凝血纤溶实验指标在DIC诊断中的应用[J].临床检验杂志,2007,25(3):225-226. 被引量:14
  • 5谢幸.妇产科学[M].8版.北京:人民卫生出版社,2012:374-386.
  • 6Oron G,Ben-Haroush A,Hod M. Serum-soluble CD40 ligand in normal pregnancy and in preeclampsia[J].Obstetrics and Gynecology,2006,(04):896-900.
  • 7Ducloy-Bouthors A S. Hémostaseet preeclampsia[J].Annales Francaisesd' Anesthésieetde Réanimation,2010,(05):121-134.
  • 8Haliloglu B,Aksungar F B,Celik A. Negative correla-tion between D-dimer and homocysteine levels during pregnancy and the postpartum period:A prospective study[J].European Journal of Obstetrics & Gynecology and Reproductive Biology,2010,(01):23-26.
  • 9Kovac M,Mikovic Z,Rakicevic L. The use of D-dimer with new cutoff can be useful in diagnosis of venous thromboembolism in pregnancy[J].European Journal of Obstetrics & Gynecology and Reproductive Biology,2010,(01):27-30.
  • 10Moresco RN,Junior RH, Cldudio Rosa Vargas L, et al. Associa tion between plasma levels of D-dimer and fibrinogen/fibrin deg radation products(FDP) for exclusion of thromboembolic disor ders[J]. J Thromb Thrombolysis,2006,21 (2) :199-202.

引证文献10

二级引证文献35

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部