摘要
目的:观察地佐辛复合氟比洛芬酯用于脊柱后路手术术后静脉自控镇痛(patient con-trolled intravenous analgesia,PCIA)的效果。方法:60例行脊柱后路内固定手术的患者,随机均分为地佐辛复合氟比洛芬酯组(DF组)、舒芬太尼组(S组),每组30例。观察两组患者术后1、4、8、12、24、36、48h在安静时及翻身运动时视觉模拟评分(VAS)、镇静程度评分(Raesay)、48h内患者自控镇痛(patient controlled analgesia,PCA)有效按压次数与实际按压次数比、患者镇痛满意度、总体评价及不良反应的发生情况。结果:两组配方均能为患者提供良好的术后镇痛,有效按压次数与实际按压次数比两组相近(P>0.05);DF组患者在翻身运动时的VAS评分、镇痛满意度及总体评价显著优于S组(P<0.05),不良反应发生率低(P<0.05)。结论:地佐辛复合氟比洛芬酯用于脊柱后路手术PCIA,镇痛效果良好,不良反应发生率低。
RESULTS：The two groups were able to provide good postoperative analgesia, the number of ef- fective compression ratio and the actual number of pressing were similar （P〉0.05）. DF group＇s VAS scores movement in the stand, patient satis- faction with pain and overall assessment of pain patients were significantly better than those in the S group（p〈0.05）, and had lower incidence of adverse reactions（P〈0.05）. CONCLUSION ： Dezocine combining with flurbiproIen can pro- vide satisfactory postoperative analgesia after posterior spinal approach, and has lower inci- dence of adverse reactions.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2012年第3期322-325,共4页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
地佐辛
氟比洛芬酯
术后镇痛
脊柱
Dezocine
Flurbiprofen
Postop-erative analgesia
Spine
