摘要
目的研究氟比洛芬酯超前镇痛在妇科手术中的镇痛作用及效果。方法50例ASAⅠ～Ⅱ级择期行妇科手术的患者，随机分为两组，每组25例。Ⅰ组（试验组）术前15min静脉缓慢注射氟比洛芬酯50mg；Ⅱ组（对照组）术前15min静脉缓慢注射生理盐水5ml。分别记录术后1、2、4、8、12、24h的视觉模拟评分法（VAs）的评分及不良反应；并在镇痛结束后对患者的镇痛效果及满意度进行统计。结果术后1、2、4、8h的VAS评分Ⅰ组均低于Ⅱ组（P〈0．05），两组的不良反应差异无统计学意义。镇痛结束后，患者对镇痛效果的满意度在Ⅱ级、Ⅳ级Ⅰ组和Ⅱ组比较差异有统计学意义（P〈0．05）。结论氟比洛芬酯用于妇科手术超前镇痛，能提高术后镇痛质量，减少不良反应的发生。
Objective To study the preemptive analgesia effect of flurbiprofen axetil during gynecological operation. Methods Fifty patients （ASA Ⅰ- Ⅱ ）were randomly assigned into two groups. The patients in group Ⅰ （n=25）received intravenous injection of flurbiprofen axetil 50 mg in 15 minutes before surgery, and those in group Ⅱ （n=25）intravenous injection of saline 5 ml. Postoperative analgesia efficacy was assessed by VAS at 1,2,4,8,12,24 hours and adverse effect were recorded after surgery. The overall satisfaction to analgesic therapy was evaluated. Results VAS in the group Ⅰ at 1,2,4,8 hours were lower than those in group Ⅱ （P 〈 0.05 ）. There were no significant difference between the two groups in adverse effects. The overall satisfaction to analgesic therapy was significantly different between two groups （P 〈 0.05）. Conclusion Flurbiprofen axetil can produce preemptive effect and reduce the adverse effect.
出处
《中国医师进修杂志》
2007年第2期19-20,24,共3页
Chinese Journal of Postgraduates of Medicine
关键词
氟比洛芬酯
超前镇痛
妇科手术
Flurbiprofen axetil
Preemptive analgesia
Gynecological operation
