摘要
目的了解脑微出血(CMB)在急性脑梗死患者中的发生率,并对其危险因素进行分析。方法选择我院2010年2月～2011年6月连续收治的82例急性脑梗死患者,根据MRI磁敏感加权成像上有无CMB分为2组,CMB组40例和无CMB组42例。比较2组患者的一般临床资料及生化指标,并进一步回归分析CMB发生的相关危险因素。结果与无CMB组比较,CMB组患者TC、TG、LDL-C明显降低,同型半胱氨酸明显升高,差异有统计学意义(P<0.05,P<0.01);CMB组脑卒中比例有升高趋势,但差异无统计学意义(P>0.05)。结论在急性脑梗死患者中CMB较常见,血浆同型半胱氨酸是CMB发生的独立危险因素。
Objective To investigate the incidence of cerebral microbleeds（CMB） in patients with acute cerebral infarction and analyze its risk factors. Methods Eighty-two patients with acute cerebral infarction admitted to our hospital from February 2010 to June 2011 were divided into CMB group（n=40） and non-CMB group（n=42） according to their MRI susceptibility-weighted imaging and CMB. General clinical data and biochemical variables were compared between two groups. Relative risk factors for CMB were analyzed by regression analysis. Results The total cholesterol, triglyceride, and LDL-C levels were significantly lower while the plasma homocysteine level was significantly higher in CMB group than in non-CMB group（P〈0.05 ,P〈O. 01）. No significant difference was found in the incidence of cerebral stroke between the two groups although it tended to increase in CMB group（P〉0.05）. Conclusion CMB usually occur in patients with acute cerebral infarction and plasma homocysteine level is an independent risk factor for it.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2012年第4期386-389,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
合肥市科技计划项目(2011-25)
关键词
脑梗死
脑出血
磁共振成像
高半胱氨酸
高血压
纤维蛋白
年龄因素
危险因素
brain infarction
cerebral hemorrhage
magnetic resonance imaging
homocysteine
hypertension
fibrin
age factors
risk factors
