摘要
本文从临床及体内杀菌活性两方面观察了Unasyn的抗菌效果。10名健康受试者静脉滴注Unasyn 3克(含氨苄青霉素 2克,舒巴克坦 1克),对产酶金葡球菌、变形杆菌、不动杆菌和肺炎杆菌等血清杀菌活性显著高于氨苄青霉素 2克。 Unasyn 6克/日( 5～ 7天)静脉注射用于11名呼吸系感染患者,总有效率90.9％,对肝、肾、凝血功能等无不良影响。
The Serum bactericdal activity (SBA) was studied in ten health volunteers receiving Ampicillin 2 g or Unaszn 3g(containing AmpicilJin 2g and Sulbactam lg) given iv.SBA of Unasyn against the strains of S. aureus,P. mirabilis, Acineto-bacter calocaceticus and K, pneumonia were significantly higher than Ampicillin.
Eleven patients suffered from pneumonia or airway infection were treated by Una-syn. The total efficacy rate was 90.9%, and no toxicity was found in liver kidney and in blood coagulation mechanism.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
1990年第4期291-295,共5页
Chinese Journal of Antibiotics
