摘要
目的 了解我国健康人群丙型肝炎病毒感染现状.方法 采用北京万泰生物药业的HCV EIA诊断试剂检测人群血清丙型肝炎病毒（丙肝,HCV）IgG抗体.结果 六省市（区）人群血清共9 538份,HCV抗体阳性数37份,总阳性率为0.39％,其中北京人群阳性率0.23％,黑龙江人群为0.74％,山东人群为0.26％,宁夏人群为0.10％,甘肃和四川人群阳性率均为0.44％.对37例HCV阳性者性别及年龄分析,男性19例占51.35％,女性18例占48.65％,＜10岁年龄组1例,占2.70％,10～19岁组5例,占13.51％,20～29岁4例占10.81％,30～39岁组6例,占16.22％,40～49岁组9例,占24.32％,≥50岁有12例占32.43％.对HCV阳性者重叠其他型别肝炎病毒感染分析,单独HCV阳性2例,占5.41％,伴有HAV-IgG抗体阳性35例,占94.59％,伴有HEV-IgG抗体阳性10例,占27.03％,伴有HBsAg、HBcAb和HbeAb阳性者2例,占5.41％,该2例HAV和HEV抗体也阳性.结论 六省市（区）人群HCV感染率均在1％以下,感染者年龄以50岁以上最高,决大多数HCV阳性者重叠有其他型别的肝炎病毒感染.
Objective To investigate the seroprevalence of hepatitis C viruse infection in the human population in six regions of Beijing,Heilongjiang,Shandong,Ningxia,Gansu and Sichuan in China.Methods ELISA was used for detecting anti-HCV IgG of the serum samples.All sample were collected in 2006-2008 in six areas.Results 9538 samples were detected.The total positive rate of anti-HCV was 0.39%（37）,0.23% （3/1328） in Beijing,0.74% （12/1629） in Heilongjiang,0.26% （5/1962） in Shandong,0.1% （ 1/1000 ） in Ningxia,0.44% in Gansu （ 9/2037 ） and Sichuan （ 7/1582 ）,respectively.The 37 positive samples at the sex were 19 （51.35%） of man and 18 （48.65%） of female.At the age group were 1 （2.70%） of〈 10 years old,5 （13.51%） of 10-19 years old,4 （10.81%） of 20-29 years old,6 （16.22% ） of 30-39 years old,9 （24.32% ） of 40-49 years old,12 （32.43%） of≥ 50 years old.The positive samples were detected anti-HAV-IgG,anti-HEV-IgG and HBsAg/ HBcAb /HBeAb,The positive Number was 35 （94.59%）,10 （27.03 % ） and 2 （5.41% ） respectively.Conclusions HCV infection rate in the population was 0.1% -0.74%,1/3 of≥50 years old in HCV positive.Hepatitis C virus co-infection with HAV,HEV and HBV.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
北大核心
2011年第6期448-449,共2页
Chinese Journal of Experimental and Clinical Virology
