摘要
目的：分析我院药品不良反应（ADR）的发生特点．促进临床合理用药。方法：采用回顾性分析的方法．收集我院2010年ADR报告药品种类、给药途径、ADR累及器官或系统、临床表现、ADR严重程度分级、报告ADR的部门及报告人所属医务人员类型等。结果：2010年我院共收集ADR报告152例．其中抗感染药物和心血管药物第1位和第2位：口服药物、静脉滴注药物引发的ADR分别占48.2％和47.4％；ADR临床表现以皮肤及其附件损害为主．占42.1％：新的及严重的ADR分别占7．9％和5.9％；皮肤科、药剂科和肿瘤治疗中心报告的ADR分别占24.3％、13.8％、10．5％：医师报告的ADR占71．7％。结论：开展ADR监测工作是医疗机构的重要任务．应重视与加强ADR监测与报告工作．保障患者的用药安全。
Objective： To investigate the characteristics of adverse drug reactions in our hospital and promote rational drug use in clinic. Methods： There were 152 ADR cases collected in our hospital in 2010, which were retrospectively analyzed in respect of drug categories, routes of administration, systems involved, clinical manifestations, serious degrees of ADR, and source of reports. Results： ADR reports mainly involved anti-infective drugs and cardiovascular drugs; oral medication, intravenous drugs accounted for 48.2% and 47.4% of ADRs, respectively; lesions of skin and its appendages were the main clinical manifestations, accounting for 42.1% of ADRs; new and serious ADRs accounted for 7.9% and 5.9% of ADRs; reports from department of dermatology, department of pharmacy and cancer treatment center accounted for 24.3%, 13.8% and 10.5% of ADRs; 71.7% of ADR reports were from physicians. Conclusions： ADR monitoring is an important task in medical institutions, and more attention should be paid to strengthen ADR monitoring and reporting in order to improve medication safety.
出处
《药品评价》
CAS
2011年第22期40-43,共4页
Drug Evaluation
关键词
药品不良反应:监测
分析
Adverse drug reactions
Monitor
Analysis
