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泮托拉唑预防腹部手术后应激性溃疡的疗效 被引量:6

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摘要 目的探讨泮托拉唑预防腹部手术后应激性溃疡的临床疗效。方法 2010-2011年我院收治的腹部手术患者140例,按照随机分组法分为对照组和治疗组,每组70例。对照组给予西咪替丁,治疗组给予泮托拉唑。治疗2周后对两组的临床疗效进行对比分析。结果对照组和治疗组治疗有效率分别为79.68%和95.59%,两组比较差异具有统计学意义(P<0.05)。结论泮托拉唑预防腹部手术后应激性溃疡疗效显著,不良反应较低,值得临床推广使用。
作者 颜学槐
出处 《实用药物与临床》 CAS 2012年第3期183-184,共2页 Practical Pharmacy and Clinical Remedies
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  • 1[1]Rasmussen L, Oster JE, Qvist N, et al. The effects of omeprazole on intragastric pH, intestinal motility, and gastric emptying rate[J]. Scand J Gastroenterol,1999,34(7):671-675.
  • 2[2]Fuchs KH, Fein M, Maroske T, et al. The role of 24-hr gastric pH monitoring in the interpretation of 24-hr gastric bile monitoring for duodenogastric reflux[J]. Hepatogastroenterology,1999,46(25):60-65.
  • 3[3]Kromer W, Horbach S, Luhmann R. Relative efficacies of gastric proton pump inhibitors: their clinical and pharmacological basis[J]. Pharmacology,1999,59(2):55-77.
  • 4[4]Hasselgren G, Keelan M, Kirdeikis P, et al. Optimization of acid suppression for patients with peptic ulcer bleeding: an intragastric pH-metry study with omeprazole[J]. Eur J Gastroenterol Hepatol,1998,10(7):601-606.
  • 5[5]Savarino V, Mela GS, Zentilin P, et al. Comparison of 24-hr control of gastric acidity by three different dosages of pantoprazole in patients with duodenal ulcer[J]. Aliment Pharmacol Ther,1998,12(12):1241-1247.
  • 6[6]Nishioka K, Nagao T, Urushidani T. Correlation between acid secretion and proton pump inhibitiors omeprazole and pantoprazole. Biochem Pharmacol,1999,58(8):1349-1359.
  • 7Allen ME, Kopp BJ, Erstad BL. Stress ulcer prophglaxis in the postoperative period. Am J Health Syst Pharm,2004,61 (6) :588 -596.
  • 8Messmann H, Schohnerich J. Do adrenal cortical hormones influence the pathogen-esis of stress ulcer? Dtsch Med Wochenschr,2000,125(4):99 -100.
  • 9Jung R, MacLaren R. Proton pump inhibitors for stress ulcer prophylaxis in critically ill patients. Ann Pharmacother, 2002 ,36(12) :1929-1937.
  • 10Steinberg KP. Stress-related mueosal disease in the critically ill patient: risk factors and strategies to prevent stress-related bleeding in the intensive care unit. Crit Care Med,2002, 30(6):362-364,.

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