摘要
目的探讨超声引导下经皮肝穿刺活组织病理检查在临床肝病诊疗中的意义。方法回顾性分析了吉林大学第一医院157例超声引导下经皮肝穿刺活组织病理检查病例,所有病例均为肝损害经常规检查方法未能明确诊断或临床诊断分期不明确。所有患者经临床生化学检查及影像学检查均未提示肝硬化。分为I组(HBV感染组)和II组(非HBV感染组)。结果 157例病例中,I组81例,其中IA组(ALT<2×ULN)43例,IB组(ALT≥2×ULN)38例。II组76例,其中自身免疫性肝病30例,药物性肝损害21例,脂肪性变11例,罕见病例8例,隐源性肝炎6例。结论超声引导下经皮肝穿刺活组织检查安全性较高,肝活组织病理检查在不明原因的肝损害或临床诊断分期不明确的肝损害诊断中有非常重要的价值,可减少临床漏诊及误诊,有利于明确肝损害的病因及程度。
Objective To investigate the significance of ultrasound-guided percutaneous liver biopsy in diagnosis and treatment of liver disease.Methods 157 liver biopsy pathology cases from the First Hospital of Jilin University were retrospectively analyzed.All cases with liver damage failed to confirm the diagnosis by routine examinations or the stages of clinical diagnosis were not clear.All patients were not diagnosed as cirrhosis by clinical biochemical examinations and imaging studies.All cases were divided into group I（HBV infection group） and group II（non-HBV infection group）.Results Out of 157 cases of liver biopsy pathology,81 cases are in group I,among which 43 cases are in group IA（ALT〈2ULN） and 38 ones are in group IB（ALT≥2ULN）.76 cases are in group II,which includes 30 autoimmune liver diseases;21 drug-induced liver damages;11 fatty changes;8 rare cases;6 cryptogenic hepatitis.Conclusion The security of ultrasound-guided percutaneous liver biopsy is high.There is a very important value of pathological examination of liver biopsy in diagnosing of what were failed to confirm by routine examinations or the stages of clinical diagnosis were not clear.It is useful to confirm the cause and extent of liver damage,and reduce misdiagnosis and missed diagnosis.
出处
《临床肝胆病杂志》
CAS
2012年第3期223-226,共4页
Journal of Clinical Hepatology
关键词
活组织检查
针吸
病理过程
肝疾病
biopsy
needle
pathologic prolesses
liver diseases
