摘要
胆管消失综合征(VBDS)主要指多种因素包括先天性畸形、感染性、恶性病变、缺血性、免疫性、药物、特发性、中毒性引起的病理过程使肝内胆管树结构破坏而致肝胆管局灶或弥漫性消失,临床上出现胆汁淤积综合征。近年,随着肝移植手术的成熟和发展,包括VBDS在内的胆道并发症已逐步成为肝移植术后的重要并发症。对其病因、临床表现、诊断、鉴别及治疗的进展进行综述,为最大可能避免其渐进过程和潜在致命结局,做出预防和早期诊断。
Vanishing bile duct syndrome（VBDS）is a local or diffuse disappearance of intrahepatic bile duct resulting from its damage, which is the result of pathological procedures induced by many reasons, they are congenital abnormality, infection, malignant disease, ischemic changes, immunity, drug, idiocrasy and toxication. Cholestasis syndrome will be occur in clinic aecompanying with it. Recently, with the development of liver transplantation, biliary tract complication including VBDS is gradually becoming important complication of posttransplantation of liver. This article reviews the progress about some questiones related to VBDS in many aspects sach as etiological factor, clinical manifestation, diagnosis, identity and treatment. Accordingly, we can make the best possibility to avoid its gradual process and potential fatal outcome and achieve preeantion and early diagnosis.
出处
《医学综述》
2008年第2期285-287,共3页
Medical Recapitulate
关键词
胆管消失综合征
病因学
诊断
治疗
Vanishing bile duct syndrome
Etiology
Diagnosis
Treatment
