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滤纸片干血斑技术在婴儿HIV感染早期诊断中的应用 被引量:2

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摘要 [目的]探讨滤纸片干血斑HIV-1DNA检测技术在婴儿HIV早期感染诊断中的应用。[方法]于2009至2011年在云南省红河州5所妇幼保健院,用滤纸片干血斑和罗氏HIV-1 DNA检测技术分析HIV母婴阻断项目下未满18个月的婴儿的HIV感染状况。[结果]检测249名婴儿,其中10名婴儿HIV-1 DNA阳性,与病毒载量或18月龄后的HIV抗体结果相吻合。采取母婴阻断干预措施后的婴儿感染率为3.7%,如果从孕期就开始采取干预措施的,婴儿感染率可降到0.65%,未采取任何干预措施的,婴儿感染率为16.6%。[结论]滤纸片干血斑的HIV-1 DNA检测技术的简便、快速,其定性结果与病毒载量一致,可以作为HIV母婴传播早期诊断的检测方法,可及时评估母婴阻断的效果。
出处 《卫生软科学》 2012年第3期237-238,共2页 Soft Science of Health
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