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畸形性骨炎研究进展 被引量:10

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摘要 畸形性骨炎是局限性骨重建异常的疾病 ,其病因尚未完全阐明 ,认为主要是病毒感染和遗传因素。易感基因定位于染色体 1 8q2 1 2 2 ,其确切发病机理还不清楚 ,可能由于基因突变或受损后增加破骨细胞和其前体对麻疹病毒或亚粘液病毒等的易感性而致病。治疗药物有降钙素和二膦酸盐 ,近年更多采用新一代二膦酸盐制剂能显著缓解症状 ,控制病情发展 ,且副作用较少。
机构地区 中国医学科学院
出处 《国外医学(内分泌学分册)》 2000年第1期8-11,共4页 Foreign Medical Sciences(Section of Endocrinology)
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