摘要
目的:比较黄连-厚朴药对、黄连-厚朴有效部位、盐酸小檗碱-厚朴酚不同比例的止泻、镇痛作用。方法:观察黄连-厚朴药对、黄连-厚朴有效部位、盐酸小檗碱-厚朴酚不同比例对冰乙酸致小鼠扭体反应的影响及对番泻叶致小鼠腹泻模型的影响。结果:黄连-厚朴药对1∶2、黄连-厚朴有效部位1∶2、和盐酸小檗碱-厚朴酚1:2的止泻、镇痛效果较好。结论:盐酸小檗碱-厚朴酚、黄连-厚朴有效部位和其药对具有同样的止泻、镇痛作用,且最佳组方配比为1∶2。
Objective：To compare the diarrhoea and analgesia effect of different proportions of coptis-magnolia, coptis-magnolia effective part and berberine hydrochloride-magnolol. Methods： Observe the diarrhoea and analgesia effect of different proportions of coptis-magnolia, coptis-magnolia effective part and berberine hydrochloride-magnolol by the model of acetic acid in mice writhing and senna induced diarrhea. Results： The 1：2 prescription ratio of the coptis-magnolia, coptis-magnolia effective part and berberine hydrechloride-magnolol have good effect on diarrhoea and analgesia. Conclusion： Coptis-magnolia, coptis-magnolia effective part and berberine hydrochloride-magnolol have the same diarrhoea and analgesia effect, and the best prescription ratio is 1：2.
出处
《北方药学》
2012年第3期48-49,共2页
Journal of North Pharmacy
关键词
黄连-厚朴药对
有效部位
有效成分
腹泻
镇痛
Coptis - magnolia Effective part Active principle Diarrhea Analgesia
