摘要
目的探讨IL-6和hs-CRP水平在免气腹二孔法微型腹腔镜阑尾切除术(MLA)与开腹阑尾切除术(OA)前后的变化,为评价这两种术式的效果提供科学依据。方法采用ELISA双抗体夹心法和全自动生化分析仪检测41例MLA与41例OA患者术前、术后(24 h、72 h)IL-6和hs-CRP水平。结果两组患者术前血清IL-6和hs-CRP水平差异无统计学意义(P>0.05);术后24 h两组患者血清IL-6和hs-CRP水平与术前相比均明显升高(P<0.01),并且OA组明显高于MLA组,术后72 h两组血清IL-6和hs-CRP均有所下降,而MLA组较OA组下降更显著,两组差异均有统计学意义(P<0.01)。结论免气腹二孔法腹腔镜阑尾切除术对患者的创伤更小,减少患者应激反应。
To investigate the level change of IL-6 and hsCRP after the gasless twoport minilaparoscopic appendectomy（MLA） and open appendectomy（ OA）, and provide the scientific evidence for the evaluation of effects of these two operations. Methods Fortyone cases of MLA and 41 cases of traditional OA received IL-6 and hsCRPdetection with double antibody sandwich enzymelinked immunosorbent assay （ELISA）and automatic biochemical analyzer 24 hours,72 hours before and after operation. Results There was no significant difference in preoperative serum IL-6 and hsCRP level between the two groups（P 〉0. 05）. Serum IL-6 and hs-CRP levels 24 hours after operation of these two groups significantly increased compared with those before operation（P 〈0. 01 ）. The increase of serum IL-6 and hsCRP levels of OA group was significantly higher than that of MLA group, serum IL-6 and hsCRP levels of these two groups decreased 72 hours after operation, while those of MLA group decreased more significantly compared with those of OA group, and there was significant difference （ P 〈 0.01 ）. Conclusion MLA is minimally invasive, which can reduce patients＇ stress response.
出处
《广西医学》
CAS
2012年第2期169-171,共3页
Guangxi Medical Journal
基金
广西南宁市科学研究与技术开发计划项目(南科发200902083C-2)
