摘要
嗅觉感知的起始是由嗅觉受体(olfactory receptor,OR)被气味分子激活,引起细胞内的信号转导,将气味的化学信号转变成电信号,传到更高的脑部结构,完成气味感知。OR基因属于多基因家族,编码的嗅觉受体蛋白(olfactory receptor protein)属于G-蛋白偶联受体超家族,有7个跨膜区域。嗅觉受体蛋白在嗅觉识别气味及信号传导过程中起着重要的作用。
The olfactory perception is the process that the olfactory receptor is activated by odorous molecules,which induce the transduction of signal in the cell and the chemical information is transduced into electrical impulses.After the changed signal is transmitted to the brain,the whole perception process completes.OR gene belongs to the multigene family.The coded olfactory receptor proteins belong to the G-protein-coupled receptor（GPCR） superfamily and therefore are invariably seven-transmembrane domain（7TM） protein.Olfactory receptor protein plays an important role in olfactory perception and signal transduction process.
出处
《浙江大学学报（医学版）》
CAS
CSCD
北大核心
2012年第1期117-122,共6页
Journal of Zhejiang University(Medical Sciences)
基金
国家自然科学基金青年科学基金项目(31000448)
