摘要
目的探讨在线尿素清除率监测（OCM）与尿素清除指数（Kt／V）在评价血液透析充分性中的价值及相关性分析。方法48例在成都军区昆明总医院血透中心行维持性血液透析的终末期肾衰患者，采用德国贝朗Dialog＋血透机自带OCM监测仪检测尿素清除指数（Kt／V），同时在透前、透后抽血，应用尿素动力学-室可变容积模型检测Kt／V计算值，并对OCM检测值和Kt／V计算值进行相关性分析；探讨OCM与尿素清除指数（Kt／V）在评价血液透析充分性中的作用。结果OMC与Kt／V比较差异无统计学意义（1．467±0．318v81．629±0．262，P〉0．05），但两者呈正相关（r=0．539，P〈0．01）。结论OCM检测值与应用尿素动力学-室可变容积模型计算的Kt／v值相近，二者关系密切相关，可以作为评价尿毒症血透患者血液透析充分性的一项较可靠指标。
Objective To evaluate the adequacy of hemodialysis by online clearance monitoring （OCM） and Kt/V of correlation analysis. Methods The Kt/V values of 48 maintenance hemodialysis pa- tients in the Department of Nephrology of General Hospital of PLA were accessed by both OCM of Germany BeiLang Dialog ＋ hemodialysis machine and single,pool urea kinetic model. The Kt/V calculation value was also checked by the urea dynamics - room variable volume model. The results generated at different timepoint were compared, including at the real time, before and after appearing through blood by On - line Clearance Monitoring, and correlation analysis of Kt/~ value was performed. Results There was no signif- icant difference on evaluating the level of Kt./v by these two methods. The relationship between the results of the two methods was significantly positive related. （ r = 0. 539, P 〈 0. 01 ）. Conclusions During hemodi- alysis, the OCM option provides an accurate tool for continuous on-line monitoring of urea clearance.
出处
《中国医师杂志》
CAS
2012年第2期177-178,181,共3页
Journal of Chinese Physician
