摘要
目的观察不同选穴原则针刺治疗寻常性痤疮的不同疗效。方法将51例寻常性痤疮受试者按完全随机的方法分为局部选穴组、远端选穴组和局部兼远端选穴组，并设10例正常对照组，观察各组针刺前后血清花生四烯酸（AA）、游离睾酮（FT）、性激素结合球蛋白（SHBG）水平的变化。结果治疗后，局部选穴组、远端选穴组、局部兼远端组血清AA[分别为（20．56±5．28）ug／L、（18．86±5．70）ug／L、（14．62±3．06）ug／L]，SHBG[分别为（333-31±87．96）nmol／L、（332．02-4-87．82）nmol／L、（273．02±61．74）nmol／L]检测水平均接近正常，与正常对照组比较，差异无统计学意义p〉0．05），FT仅局部兼远端组（5．62±1．98）nmol／L与正常对照组比较，差异无统计学意义（P〉0．05）。AA下降水平局部兼远端选穴组优于局部选穴组（P〈0.01）。结论针刺可有效改善寻常性痤疮的炎症因子和相关雄激素水平，不同选穴原则的针刺对部分指标的改善有较大差异性。
Objective To evaluate the treatment of acne vulgads with acupuncture by different methods of point selection. Methods 51 cases of ache vulgaris were randomly recruited into local point selection group, distal point selection group and combination of local and distal point selection group. 10 cases of healthy people were recruited for normal control group. Serum arachidonic acid （AA）, free testosterone （FT）, and sex hormone binding globulin （SHBG） levels were observed in all treatment groups. Results After the treatment, serum AA was （20.56±5.28）upg/L, （18.86±5.70）pg/L and （14.62±3.06）ug/L, while SHBG was （333.31＋87.96） nmol/L, （332.024±87.82） nmol/L and （273.024±61.74） nmol/L respectively in local point selection group, distal point selection group and combination of local and distal point selection group, both showing no significant difference than the normal control group （P〉0.05）. There was no significant difference in FT value between the combination of local and distal point selection group （5.624±1.98） nmol/L and the normal control group （P〉0.05）. The decrease of AA in the combination of local and distal point selection group was between than the local point selection group （P〈0.01） . Conclusion Acupuncture can effectively improve the level of inflammatory factors and androgen of the acne vulgaris. Different methods of point selection of acupuncture on the improvement of some indicators were quite different, which laid the foundation for the best compatibility of acupuncture treatment in acne vulgaris.
出处
《国际中医中药杂志》
2012年第3期200-202,共3页
International Journal of Traditional Chinese Medicine
基金
南京中医药大学针药结合实验室开放课题（项目编号：KJA200915）
