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吸入噻托溴铵对稳定期慢性阻塞性肺疾病患者生活质量影响的观察 被引量:2

Observation of influence by inhaling Tiotropium Bromide to the patients' quality of life with chronic obstructive pulmonary disease in stable condition
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摘要 目的探讨噻托溴铵干粉剂治疗对轻中度稳定期慢性阻塞性肺疾病(COPD)患者生活质量的影响。方法 60例轻中度稳定期COPD患者规律吸入噻托溴铵干粉剂前后,分别进行FEV1、FEV1/FVC等肺功能指标检测、用CAT量表进行生活质量评估。结果规律治疗后患者CAT评分明显减低,与FEV1、FEV1/FVC的增加相一致。结论规律吸入噻托溴铵可以改善轻中度稳定期COPD患者的生活质量。 Objective To discuss the effect of the treat by Tiotropium Bromide dry powder to patients' quality of life in stable condition with mild and moderate chronic obstructive pulmonary disease. Methods Detected the pulmonary function indicatrix such as FEVland FEV1/FVC of sixty patients with mild and moderate chronic obstructive pulmonary in stable condition respectively before and after they inhaled Tiotropium Bromide dry powder. Used CAT scale to assess their quality of llfe. Results CAT score of them decreased significantly with the improvement of the difficulty in breathing and exercise tolerance after the patients were treated regular- ly. Conclusion Inhaling Tiotropium Bromide dry powder regularly can improve patients' quality of life with mild and moderate COPD in stable condition.
出处 《中国现代药物应用》 2012年第3期12-13,共2页 Chinese Journal of Modern Drug Application
关键词 肺疾病 生活质量 噻托溴铵 Pulmonary disease Quality of life Tiotropium Bromide
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  • 1Celli BR,Thomas NE,Anderson JA,et al.Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease:results from the TORCH study.Am J Respir Crit Care Med,2008,178(4):332-338.
  • 2Jones PW,Harding G,Berry P,et al.Development and first validation of the COPD Assessment Test.Eur Respir J,2009,34:648 -654.
  • 3Joo MJ,Au DH,Fitzgibbon ML,et al.Respir Med,2010,104:246-252.
  • 4Buhling F,Lieder N,Kuhlmann U C,et al.Tiotropium suppresses acetyl-Choline induced release of chemotactic mediators in vitro.Respir Med,2007,101(11):2386-2394.
  • 5柳涛,蔡柏蔷.一种新型的生活质量评估问卷:慢性阻塞性肺疾病评估测试[J].中国医学科学院学报,2010,32(2):234-238. 被引量:175

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