摘要
本文在Shay氏溃疡模型基础上,研究了禁食时间对大白鼠实验性胃溃疡的影响。结果表明。禁食大白鼠,在结扎幽门18hr后,出现不同程度的胃溃疡,其程度与禁食时间呈正相关,而与胃酸分泌量呈负相关。故禁食因素是该溃疡模型产生的重要原因。
On the basis of Shay's ulcer model, we have studied the effects of food re. striction time on the experimental gastric ulcer in rats. The results indicat that each restricted group forms gastric ulcer after ligation of pylorus 18 hr. There are a postive correlation between the restricted time and the severity of gastric ulcer, and a negative correlation between the severity of gastric ulcer and the amount of gastric acid secretion. We suggested that Shay's ulcer model does not belong to peptic ulcer, but belonges to one of the stress ulcers. The restricted time may play an important role in the mechanism for this ulcer model.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1990年第1期56-59,共4页
Chinese Journal of Pathophysiology
关键词
胃溃疡
禁食
Fasting
Ulcer, gastric