摘要
目的研究慢性阻塞性肺疾病稳定期中医证型与红细胞免疫功能的相关性。方法按《慢性阻塞性肺疾病(COPD)诊治指南(2007年修订版)》和中医辨证标准收治肺气虚、脾气虚、肾气虚组COPD稳定期的患者和正常对照组各30例,分析4组的红细胞免疫(RBC-C3bRR、RBC-I-CR)差异。结果 COPD组RBC-C3bRR和RBC-ICR与正常对照组比较,差异具有显著的统计学意义;在肺气虚、脾气虚、肾气虚3个证型中,差异也有显著的统计学意义,肺气虚组→脾气虚组→肾气虚组RBC-C3bRR逐步减少,RBC-ICR逐步增高。结论 RBC-C3bRR、RBC-ICR可作为COPD稳定期患者辨证分型、病情预后、疗效判定的参考指标。
Objective To study the correlation between erythrocyte immune function and TCM syn- dromes of chronic obstructive pulmonary disease （COPD） patients at stable stage. Methods COPD patients with lung Qi deficiency syndrome, spleen Qi deficiency syndrome and kidney Qi deficiency syndrome at stable stage were selected according to the diagnosis and treatment guidelines of COPD and criteria of TCM syndrome differentiation, and healthy people as control. The differences of red blood cell immune （RBC-C3bRR, RBC-ICR） among various syndromes were analyzed. Results There were significant differences in RBC- C3bRR rate and RBC-ICR rate between COPD patients and healthy people. There were also significant differences in RBC-C3bRR rate and RBC-ICR rate among three syndromes, the RBC-C3bRR rate of lung Qi deficiency syndrome was the highest and that of kidney Qi deficiency syndrome was the lowest, and the RBC-ICR rate of kidney Qi deficiency syndrome was the highest and that of lung Qi deficiency syndrome was the lowest. Conclusion Combined determination of RBC-C3bRR and RBC-ICR can be regarded as the reference index for the syndrome differentiation, prognosis and therapeutic effect judging of COPD patients at stable stage.
出处
《福建中医药大学学报》
2012年第1期1-3,共3页
Journal of Fujian College of Traditional Chinese Medicine
基金
福建省科技厅资助课题(2009R10007-4)
