摘要
对氯苯甲酰氯分别与苯、氯苯和氟苯经Friedel-Crafts酰化反应合成了4-氯二苯酮(CBP)、4,4’-二氯二苯酮(DCBP)和4-氯-4’-氟二苯酮(CFBP),收率都在93%以上,粗品含量在98%以上。所有产品均经熔点、HPLC和NMR氢谱表征。DCBP和CFBP的合成,实验显示二氯乙烷作溶剂的结果较佳。
Benzene, chlorobenzene and fluorobenzene were acylated by Friedel-Crafts, respectively, with 4-chloro- benzoyl chloride to obtain 4-chlorobenzophenone（CBP）, 4,4 ＇-dichlorobenzophenone （DCBP） and 4-ehloro-4 ＇-fluorobenzo- phenone（CFBP） in over 930%yields. The products were characterized by melting points, TLC, HPLC and 1H NMR spectroscopy. The dichloroethane was an optimal solvent for both DCBP and CFBP syntheses.
出处
《化工新型材料》
CAS
CSCD
北大核心
2012年第2期87-90,共4页
New Chemical Materials
基金
浙江省教育厅重点资助项目(Z201122244)
衢州市科技局资助项目(20111050)
