摘要
目的了解泌尿生殖道支原体感染及对不同抗生素的药敏情况。方法采用支原体培养鉴定药敏一体化试剂盒对26 060例疑为泌尿生殖道感染患者的泌尿生殖道分泌物进行检测。结果检出支原体感染10481例,阳性率为40.22%。其中溶脲脲原体(Uu)感染9 366例(89.36%),人型支原体(Mh)感染109例(1.04%),溶脲脲原体、人型支原体(Uu+Mh)合并感染1006例(9.60%)。药敏结果显示,Uu单独感染及Uu+Mh合并感染对交沙霉素、强力霉素、美满霉素敏感,喹诺酮类与大环内酯类药物耐药率下降。Uu+Mh合并感染呈耐药谱广、耐药率高特点。结论 Uu是引起泌尿生殖道感染的主要支原体,Uu+Mh合并感染耐药性增加,交沙霉素、强力霉素和美满霉素可作为治疗支原体感染的首选药物。
Objective To understand the mycoplasma infection in the urogenital tract and the sensitivity of different antibiotics. Methods The culture, identification and susceptibility integration kit was used for testing the urogenital tract secretions from 26 060 cases of suspected urogenital tract infection. Results Mycoplasma infections were detected in 10 481 cases, the positive rate was 40. 22%, including Ureaplasma urealyticum（Uu） infection in 9 366 cases（89. 36% ）, Mycoplasma hominis（Mh） infection in 109 cases（1.04% ）, Uu and Mh mixed infection in 1 006 cases（9. 60% ）. The results of drug susceptibility test showed： Uu infection, Uu and Mh mixed infection were all sensitive to josamycin, doxycycline and minocycline. The resistance rates of guinolones and macrolides were declining. Uu and Mh mixed infection showed broader resistance spectrum and higher resistance rate. Conclusion Uu is the major mycoplasma for urinary tract infection, Uu and Mh mixed infection will increase drug resistance. Josamycin, doxycycline and minocycline can be the preferred choices for treatment of mycoplasma infection.
出处
《中国临床新医学》
2012年第2期122-126,共5页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
溶脲脲原体
人型支原体
药物敏感性
耐药率
泌尿生殖道感染
Ureaplasma urealyticum（Uu）
Mycoplasma hominis（Mh）
Drug susceptibility
Resistance rates
Urogenital mycoplasma infection
