摘要
研究糠秕孢子菌对培养角质形成细胞产生细胞因子的影响及电镜观察。结果发现糠秕孢子菌能刺激角质形成细胞分泌IL 1α的量逐渐增加。与对照组相比均有显著差异。但IL 2、IL 4、IL 10、TNF α、IFN γ等的分泌量与对照组相比 ,统计学处理无显著性差异。电镜观察显示 ,共同培养24h后 ,角质形成细胞发生变性坏死。
The production of cytokines by the keratinocytes co cultured with P.orbiculare were studied, and the structure of keratinocytes was observed by electron microscope(EM).The results showed that P. orbiculare could stimulate the co cultured keratinocytes to produce IL 1αwhich increased significantly, but the production of IL 2,IL 4,IL 10,TNF α,IFN γ showed no significant changes. Degenerative necrosis of the co cultured keratinocytes was observed 12h after co culture with P.orbiculare uuder EM.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2000年第1期1-3,共3页
Journal of Clinical Dermatology
