摘要
目的 :通过扫描电镜观察透明质酸钠和醋酸强的松龙对免颞下颌关节表面的作用。方法 :在 2 0只未成年日本大耳白兔的右侧颞下颌关节下腔分别注射透明质酸钠和醋酸强的松龙。术后第 1、3、7、14d分批处死各组白兔 ,将标本处理后用扫描电镜观察。结果 :扫描电镜观察发现醋酸强的松龙使髁突表面和关节盘下腔面的表面凝胶样物质分布不均匀 ,出现部分区域表面凝胶样物质减少甚至消失 ,部分区域凝胶样物质聚集成团 ;而透明质酸钠不改变关节表面凝胶样物质的分布。结论 :醋酸强的松龙可破坏颞下颌关节表面的超微结构 ,透明质酸钠对颞下颌关节表面的超微结构无损害作用。
Objective:To evaluate the different effects of sodium hyaluronate and prednisolone on the surface of rabbits′ temporomandibular joints. Methods: 20 juvenile Japanese large ear rabbits were divided into 5 groups, including one control group and the other 4 experimental groups. In these groups, half of their right inferior cavity of temporomandibular joints were injected with sodium hyaluronate(25 mg/ml,0.1 ml), while others were injected with prednisolone(1%,0.1 ml), then the rabbits were killed on the 1st, 3rd, 7th,and 14th days after injection. The specimens were evaluated by scanning electron microscope (SEM) to compare the different effects on the inferior superfacial structure of the articular disc and the surface of the condyle. Results: Prednisolone could change the uniform distribution of the agglutinating substance on the inferior superfacial of the articular disc and the surface of the condyle. In the 1st day and the 3rd day groups, the agglutinating substance decreased in some areas and gathered in other areas. In the 7th day group, the distribution of the agglutinating substance on the inferior superfacial of the articular disc and the surface of the condyle were more regular than that of the 1st day and the 3rd day groups. In the 14th day group, the distribution of the agglutinating substance were almost as the same as that of the control group. But sodium hyaluronate didn't change the uniform distribution of the agglutinating substance in every group. Conclusion: Prednisolone can change the uniform distribution of the agglutinating substance on the inferior superfacial of the articular disc and the surface of the condyle, while sudium hyaluronate don't have this effect.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2000年第1期16-19,共4页
West China Journal of Stomatology
关键词
颞下颌关节
透明质酸钠
强的松龙
兔
articular disc\ \ condyle\ \ intra articular injection\ \ sodium hyaluronate\ \ prednisolone
