摘要
目的检测正常中晚期孕妇的凝血四项及D-二聚体指标,了解正常中晚期孕妇的凝血与纤溶功能状态及临床意义。方法凝血四项测定均为凝固法,D-二聚体为免疫比浊法。在Sysmex CA7000全自动血凝仪上进行检测。结果正常妊娠中晚期孕妇与正常非孕妇女对照组比较,PT、APTT时间明显缩短(P<0.05);FIB显著增高(P<0.01);TT差异不明显(P>0.05);D-二聚体水平差异有统计学意义(P<0.05)。结论妊娠中晚期由于凝血功能增强,抗凝及纤溶功能减弱,出现妊娠期高凝状态,有利于产后快速有效止血。产前凝血功能的检测,对预防产科并发症(如DIC及羊水栓塞等)有重要的临床意义。
Objective To detect the result of four items blood coagulation and plasma D - dimer in healthy women in mid - late women, so as to understand their coagulation and fibrinolysis. Methods Four items blood coagulation were assayed with coagulation method, and D - dimer with immune - turbidity method. Both were tested on sysmex Ca - 7000 full - Au- tomatic coagulation analyzer. Results Compared with the healthy non - pregnant women, women in mid - late pregnancy had shorter PT and APTF（ P 〈 O. 05 ）, and higher FIB （P 〈 O. 01 ）. There was no evident difference on TI＇ （P 〉 0.05 ）. The significant difference was also found in D - dimer level between the two groups （P 〈 0.05）. Conclusions Due to en- hanced coagulation and decreased fibrinolytic activity, hypercoagulability usually occurs in mid -late pregnancy, which is useful to stop post - partum bleeding rapidly and effectively. Therefore, it is clinically important to examine the coagulation function prenatally, especially to avoid obstetric complications such as DIC and amniotic fluid embolism.
出处
《社区医学杂志》
2012年第2期16-17,共2页
Journal Of Community Medicine
关键词
中晚期孕妇
凝血四项
D-二聚体
women in mid - late pregnancy
four items of blood coagulation
D - dimer
