摘要
目的优选复方雪莲风湿凝胶膏提取工艺。方法采用正交试验设计,分别以蛇床子素含量、姜黄素含量和浸膏收率为指标,优化雪莲等7味药材的提取工艺;以没食子酸含量和浸膏收率为指标,优选土元和五倍子2味药的提取工艺。结果 7味药最佳提取工艺为10倍量80%乙醇,提取3次,每次1 h;2味药最佳提取工艺为10倍量水,提取3次,每次2.5 h。结论优选的提取工艺稳定、可行。
OBJECTIVE To optimize the extraction process of Compound Xuelian Cataplasm. METHODS Orthogonal experimental design was used for the optimization, the extract yield, the content of osthole and curcumin were taken as the indexes in extracting process of seven herb medicines; the extract yield and the content of gallic acid were taken as the indexes in extracting process of two herb medicines. RESULTS The optimum extraction progress was as follows： seven herb medicines were extracted 3 times for 1 hour with 10 times amount of 80% alcohol; two herb medicines were extracted 3 times for 2.5 hour with 10 times amount of water. CONCLUSION The optimum extraction process was stable and feasible.
出处
《中国现代应用药学》
CAS
CSCD
2012年第2期129-133,共5页
Chinese Journal of Modern Applied Pharmacy
基金
新疆自治区科技支疆项目(201091155)
