摘要
目的:探讨慢性荨麻疹患者外周血T淋巴细胞水平变化的意义。方法:分别检测并比较正常人群与慢性荨麻疹患者外周血CD3+、CD3+CD4+、CD3+CD8+、CD3+CD4+/CD3+CD8+等指标水平情况;检测并比较慢性荨麻疹患者治疗前后治愈组、显效组、进步组及无效组外周血CD3+、CD3+CD4+、CD3+CD8+、CD3+CD4+/CD3+CD8+等指标水平变化情况。结果:慢性荨麻疹患者外周血CD3+、CD3+CD4+等指标明显低于正常组;CD3+CD8+、CD3+CD4+/CD3+CD8+与正常组无明显差异。治疗前后外周血CD3+、CD3+CD4+等指标水平明显变化,且CD3+、CD3+CD4+指标变化情况与疗效成正相关关系。结论:外周血T淋巴细胞可以作为观察临床疗效的有效指标。
Objective：To observe the influence of T-lymphocyte subgroup in patients with chronic urticaria.Methods：Divide all the case into two groups：group one was normal group,the other was patient＇s group.T-lymphocyte subgroup（including CD3＋、CD3＋CD4＋、CD3＋CD8＋ and the ratio of CD3＋CD4＋/CD3＋CD8＋） was measured between two groups and conpared before and after treatment in patient＇s group.Results：CD3＋ and CD3＋CD4＋ in patient＇s group were lower than normal group,and there were significant difference between two groups（P 0.05）,while there were no significant difference in CD3＋CD8＋、the ratio of CD3＋CD4＋/CD3＋CD8＋（P 0.05）.In patient＇s group：CD3＋、CD3＋CD4＋ were significant difference between before and after treatment,and can be negative correlation with curative effect.Conclusion：T-lymphocyte subgroup in patients with chronic urticaria might play an important role in clinical observation.
出处
《实用中西医结合临床》
2012年第1期4-5,共2页
Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
关键词
慢性荨麻疹
T淋巴细胞
疗效观察
T-lymphocyte subgroup
Chronic urticaria
Clinical observation
