摘要
癫痫是儿童常见的神经系统疾病,儿童癫痫在病因、临床表现及治疗上明显不同于成年癫痫,抗癫痫药物(AEDs)的药动学特点也不同于成人。另外,癫痫发作及AEDs均可影响患儿的行为、学习、教育、社交及情感发育。随着AEDs的不断创新和扩展以及人们对癫痫及癫痫综合征认识的深入,近年来有关难治性癫痫的治疗取得一些突破性进展。目前治疗难治性癫痫的方法主要有药物、手术、迷走神经刺激术、生酮饮食以及病因与心理治疗等。
Epilepsy is a common nervous system diseases seen in children,which is obviously different from adults′epilepsy in pathogeny,clinical feature and therapy,the pharmacokinetics characteristics of anti-epilepsy drugs（AEDs）in children are different from adults too.Besides,both epileptic seizure and AEDs affect children′s behaviour,learning,education,social contact and development of emotion.Recently,with continuous innovations and expanding,and people have known more about epilepsy and epileptic syndrome,there is some breakthrough in the treatment of intractable epilepsy.Nowadays,the main treatment of intractable epilepsy are drugs,operation,vagus nerve stimulation,ketogenic diet and psychological cure.
出处
《医学综述》
2012年第1期91-93,共3页
Medical Recapitulate
关键词
难治性癫痫
抗癫痫药物
治疗方案
治疗药物监测
Intractable epilepsy
Anti-epilepsy drugs
Therapeutic solution
Therapeutic drug monitoring
