摘要
目的分析药物难治性癫痫的手术效果,探讨术后感染相关影响因素,为临床的预防和治疗提供相关依据,提出相关预防干预措施,从而降低感染的发生。方法回顾性分析医院2008年9月-2012年8月行手术治疗并且可以随访1年以上的87例、年龄≤14岁药物难治性癫痫患儿的临床资料,分析手术的效果,并对术后感染的相关影响因素进行分析,从而提出合适的护理干预措施。结果按照Engel分级法Ⅰ级45例、Ⅱ级16例、Ⅲ级14例、Ⅳ级12例,患儿发病年龄、病程、发病频率、复杂部分性发作、单侧颞叶切除等对手术效果有影响;而手术时间、肝功能异常、颅内置管时间、腰椎蛛网膜下穿刺次数、未预防性应用抗菌药物等原因导致术后的感染。结论手术治疗药物难治性癫痫安全有效,其术后感染的因素复杂多样,采取合理的临床及护理预防干预措施可以有效减少感染的发生率。
OBJECTIVE To observe the therapeutic effect of refractory epilepsy and explore influencing factors for postoperative infections so as to provide guidance for clinical prevention and treatment, put forward corresponding intervention measures, and reduce the incidence of infections. METHODS A total of 87 children （ aged no more than 14 years old ） with refractory epilepsy who underwent the surgical treatment from Sep 2008 to Aug 2012 and received the follow-up more than one year were enrolled in the study, then the clinical data of the subjects were retrospectively analyzed, the effect of the surgery was analyzed, the related influencing factors for the postopera- tive infections were observed so as to put forward appropriate nursing interventions. RESULTS According to the Engel classification, there were 45 cases of grade Ⅰ, 16 cases of grade Ⅱ , 14 cases of grade Ⅲ, and 12 cases of grade Ⅳ. The surgical effect could be influenced by the onset age, course of disease, frequency of onset, complex partial seizures, and unilateral temporal lobe resection; however, the operation duration, abnormal liver function, intracranial catheter indwelling time, frequency of lumbar subarachnoid puncture, and without prophylactic use of antibiotics were the causes of the postoperative infections. CONCLUSION The surgery is more effective and safer than the drug therapy in treatment of the refractory epilepsy, the influencing factors for the postoperative infec- tions are complex and diversified. It is an effective way to take appropriate nursing interventions so as to reduce the incidence of infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第13期3352-3353,3356,共3页
Chinese Journal of Nosocomiology
基金
国家自然科学基金资助项目(81235034)
关键词
难治性癫痫
儿童
手术
感染
危险因素
干预措施
Refractory epilepsy
Child
Surgery
Infection
Risk factor
Intervention measure
