摘要
目的探讨不同手术方式对鼻腔、鼻窦恶性黑色素瘤预后的影响,提高鼻腔、鼻窦恶性黑色素瘤患者的生存率。方法回顾性分析12例原发性鼻腔、鼻窦恶性黑色素瘤患者的临床表现、诊断、不同手术方式的选择及随访结果。结果 12例完整随访病例中,10例接受以手术为主治疗。鼻内镜手术(术式一)3例:1年生存率为100.00%(3/3),2年生存率为33.33%(1/3),5年生存率为0.00%(0/3);鼻内镜辅助鼻侧切开术(术式二)7例:1年生存率为100.00%(7/7),2年生存率为71.43%(5/7),5年生存率为28.57%(2/7)。术后患者中4例(40.00%)出现局部复发,6例(60.00%)出现远处转移。结论采用鼻内镜辅助鼻侧切开术治疗鼻腔、鼻窦恶性黑色瘤的术后生存率较高,是较好的术式选择之一。
Objective To investigate the prognosis of different surgical options in patients with sinonasal malignant melanoma (SMM). Methods Twelve SMM cases were analyzed retrospectively with clinical manifestations, diagnosis, treatment and follow-up results. Results Among 12 cases of complete follow-up cases, 10 patients received treatment based on surgery. Three cases were treated by endoscopic sinus surgery (surgical one):The 1-, 3-, and 5-year survival rates were 100.00%, 33.33%, and 0.00%. The other seven cases were treated by nasal endoscopic assisted lateral rhinotomy (surgical two):The 1-, 3-, and 5-year survival rates were 100.00%, 71.43%, and 28.67%. The cases of local recurrence and distant metastasis were 4 and 6. Conclusions SMM is a rare malignant tumor with poor prognosis. Extensive, thorough first operation resection is the treatment of the key, nasal endoscopic assisted lateral rhinotomy is a better selection of operation.
出处
《全科医学临床与教育》
2012年第1期22-24,共3页
Clinical Education of General Practice
关键词
鼻肿瘤
恶性黑色素瘤
预后
nose neoplasms
malignant melanoma
prognosis