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HBV相关疾病患者自身抗体研究进展 被引量:4

Review of autoantibodies in patients with HBV-related diseases
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摘要 乙型肝炎病毒(hepatitis B virus,HBV)感染可致患者免疫紊乱,并产生自身抗体,包括器官特异性自身抗体和器官非特异性自身抗体。器官特异性自身抗体主要有抗肝特异性脂蛋白(liver specific lipoprotein,LSP)及抗肝细胞膜抗原(liver membrane antigen,LMA),器官非特异性自身抗体包括抗核抗体(anti-nuclear antibody,ANA)、抗平滑肌抗体(an-ti-smooth muscle antibody,ASMA)、抗细胞骨架抗体(anti-cytoskeleton,CS)、抗线粒体抗体(anti-mitochondria antibody,AMA)等。对自身抗体的检测有利于分析和评价乙型肝炎(简称乙肝)患者体内自身免疫状况,并为临床治疗方案的制定提供参考依据。 Hepatitis B virus(HBV) infection can cause immune disorders,and produce their own antibodies,including organ-specific autoantibodies and organ non-specific autoantibodies.Organ specific autoantibodies are mainly anti-LSP and an-ti-LMA and non-organ specific autoantibodies include anti-nuclear antibody(ANA),anti-cytoskeleton(CS),anti-smooth muscle antibody(ASMA),anti-mitochondria antibody(AMA),etc.The detection of autoantibodies benefits the analysis and evaluation of the body own immune status in the patients with hepatitis B and provides reference evidence for formulating the treatment scheme in clinic.
作者 赵海琳
出处 《现代医药卫生》 2012年第1期89-90,共2页 Journal of Modern Medicine & Health
关键词 乙型肝炎 自身免疫 器官特异性自身抗体 器官非特异性自身抗体 Hepatitis B Autoimmune Organ-specific autoantibodies Organ non-specific autoantibodies
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