摘要
目的探讨玉屏消风散加减治疗慢性荨麻疹的临床疗效。方法 82例患者经数字随机法分为治疗组和对照组。治疗组42例口服玉屏消风散加减治疗,1剂/d,水煎分两次服用;对照组40例口服氯雷他定片,10mg/d;两组均连续服用30d为一个疗程。观察两组1个月疗程内的疗效和不良反应及随访2个月内临床复发情况。结果治疗1个月后,治疗组总有效率为85.71%,对照组总有效率为82.50%,两组总有效率比较差异无统计学意义(P>0.05)。随访2个月后,治疗组26例痊愈患者有8例复发,对照组27例痊愈患者中有16例复发,差异有统计学意义(P<0.05)。治疗组不良反应发生率为9.52%,对照组为12.5%,差异无统计学意义(P>0.05)。结论玉屏消风散加减是治疗慢性荨麻疹的有效方药,近期疗效和安全性与氯雷他定相当,且有更好的控制复发的效果。
Objective To evaluate the clinical efficacy of modified Yu-ping-xiao-feng decoction in the treatment of chronic urticaria（CU）.Methods Eighty-two patients were randomly divided into the study group and the control group.Patients in the study group（n=42） had oral administration of modified Yu-ping-xiao-feng decoction,while whose in the control group（n=40） were treated by loratadin 10 mg/d,with 30 days as a course of treatment in both groups.The clinical efficacy and adverse effects were observed in the two groups after one month of treatment,and the recurrence was investigated within the follow-up of 2 months.Results The total effective rate after 1 month of treatment was 85.71% in the study group and 82.50% in the control group,with no statistically significant difference（P0.05）.During the follow-up,8 of the 26 cured patients in the study group and 16 of the 27 cured patients in the control group suffered recurrence,with statistically significant difference between the two groups（P0.05）.The incidence of adverse reactions was 9.52% in the study group and 12.5% in the control group,with no statistically significant difference between the two groups（P0.05）.Conclusion Modified Yu-ping-xiao-feng decoction is an effective prescription to CU.It has similar short-term efficacy and safety with loratadine tablets,but superior to loratadine tablets in the effect of preventing the recurrence of CU.
出处
《海南医学》
CAS
2012年第3期47-49,共3页
Hainan Medical Journal
关键词
慢性荨麻疹
玉屏消风散加减
疗效
Chronic urticaria
Modified Yu-ping-xiao-feng decoction
Efficacy
