摘要
目的研究乙型肝炎(乙肝)不同免疫模式与乙肝病毒(HBV)载量之间的关系。方法采用酶联免疫吸附试验(ELISA)检测乙肝标志物,用荧光定量PCR(FQ-PCR)测定HBV载量,并分析不同免疫模式与HBV载量之间的关系。结果 1(HBsAg)、3(HBeAg)、5(抗-HBc)与1、3阳性组HBV载量较高,90%在105 U/mL以上;1、4(抗-HBc)、5阳性与1、5组HBV载量相对较低80%在105 U/mL以下,χ2检验差异有统计学意义。结论 HBeAg作为HBV感染复制的指标来分组乙肝患者对乙肝的治疗和预防有重大意义。
Objective To study the relationship between the different immune patterns of HBV-M and the copies of HBV.Methods To detect HBV-M with the ELISA test,to determinate the copies of HBV with the technique of FQPCR,and to analyze the relationship between the different immune patterns of HBV-M and the copies of HBV.Results The copies of HBV were higher in the groups of 1(HBsAg),3(HBeAg),5(anti-HBc) and 1,3 than those of 1,4(anti-HBe),5 and 1,5;90% of the copies of HBV in the previous group was>105 IU/mL,80% of the latter group was<105 IU/mL,χ2 test showed significant differences.Conclusion HBeAg as the indicators of infection and copy of HBV to group the HBV patients has great significance to treatment and prevention of HBV.
出处
《检验医学与临床》
CAS
2012年第3期269-270,272,共3页
Laboratory Medicine and Clinic
