摘要
目的:探讨胎膜早破母血中IL-8对足月产前绒膜羊膜炎的诊断价值。方法:采用放射免疫法对30例胎膜早破和20例正常足月孕妇血IL-8进行测定,组织绒膜羊膜炎通过产后胎盘病理证实。结果:轻度、中重度绒膜羊膜炎与非绒膜羊膜炎相比均有显著性差异(P<0.01),轻度与中重度相比差异无显著性。轻度、中重度与非绒膜羊膜炎组IL-8水平分别为1.1141ng/ml,1.3287ng/ml,0.8108ng/ml。结论:母血IL-8水平可作为足月胎膜早破组织绒膜羊膜炎的一个预测指标。
Objective:To study the diagnostic value of maternal serum interleukin 8(IL 8) concentrations in patients with premature rupture of membranes (PROM) for chorioamnionitis at term.Methods:30 pregnant women with PROM at term and 20 normal pregnant women at term were enrolled.Maternal serum IL 8 were measured by radioimmunoassay. Chorioamnionitis was histopathologically confirmed after delivery.Results:The serum of maternalIL 8 with histological chorioamnionitis showed a significant increased than those without chorioamnionitis ( P <0.01). No significant differences in IL 8 levels were observed between the pregnant with mild and moderate chorioamnionitis. The level of serum IL 8 in mild stage(1.1141ng/ml).Moderate severe slage(1.3287ng/ml) and without chorioamnionitis( 0.8108 ng/ml).Conclusion:Measurement of maternal serum IL 8 is a marker for screening histological chorioamnionitis PROM at term.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2000年第1期29-30,共2页
Journal of Practical Obstetrics and Gynecology
关键词
胎膜早破
白细胞介素8
产前诊断
绒膜羊膜炎
Premature rupture of membrane
Interleukin
Prenatal diagnose
Chorioamnionitis
