摘要
乳酸被认为是糖酵解的最终代谢废物。肿瘤内乳酸的产生和堆积能促进肿瘤的生长和转移，且与肿瘤的预后不良有关。最近研究发现，肿瘤细胞也可以摄取和利用乳酸。随着肿瘤代谢和基因治疗研究的发展，已发现乳酸是十分有价值的肿瘤治疗靶点。
Lactate is considered a dead-end product of glycolysis. Its generation and accumulation promotes tumor growth and metastasis, and it is related to the poor prognosis of tumor. But recent studies have found, tumor cells can also uptake and utilize lactate. With the recent advances in tumor metabolism and gene therapy, lactate is a potential therapeutic target in tumors.
出处
《国际肿瘤学杂志》
CAS
2012年第2期111-113,共3页
Journal of International Oncology
关键词
肿瘤
碳水化合物
治疗
Neoplasms
Carbohydrates
Therapy
