摘要
目的探讨基底动脉尖综合征(TOBS)的病因、临床表现和影像学表现,加深对这种疾病的认识。方法回顾性分析38例TOBS患者的原始性资料。结果 TOBS患者以中老年为主,主要病因为脑栓塞及脑血栓形成,高危因素有高血压、糖尿病、心脏病、高血脂等,临床表现多以突然眩晕或意识障碍起病,合并眼球运动障碍及瞳孔异常、运动障碍、偏盲、可伴有行为异常等,CT不能清楚显示TOBS早期梗死病灶,磁共振弥散加权扫描(DWI)能准确显示TOBS梗死病灶部位及数目,磁共振血管成像(MRA)能直接反应椎动脉、基底动脉及大脑后动脉情况。结论 TOBS主要依赖临床及影像学表现综合诊断,磁共振检查对于早期诊断基底动脉综合征作用明显优于CT,DWI为早期脑梗死发现的首选检查序列,早期全面综合治疗可以提高生存率。
Objective Clinical manifestation and imaging abnormalities of the top-of-the-basilar artery syndrome（TOBS）have been summarized.Methods Clinical data of 30 patients with TOBS were reviewed retrospectively.Results Most of the cases were middle or old aged.Cerebral thrombosis and cerebral embolism were the major cause of TOBS.The high risk factors included hypertension,diabetes,heart disease,hypercholesterol,and so on.The clinical manifestation comprised the sudden vertigo or unconsciouseness with the dismovement of the eyeballs and the abnormality of the pupils,as well as the dyskinesia,partial blindness or cortical blindness and dystrophy.Computerized tomography（CT）was insensitive for acute infarction.Diffusion weighted imaging（DWI）demarcated the lesions of infarction in patients with TOBS.Magnetic resonance angiography（MRA）clearly visualized the vertebral arteries,basilar artery and posterior cerebral rteries.Conclusions Diagnosis of TOBS depends on clinical presentation and imaging changes.Magnetic resonance imaging（MRl）,especially DWI,is superior to CT in early diagnosis of TOBS.Systemic and comprehensive treatment may improve the survival rate of the TOBS patients.
出处
《医药论坛杂志》
2011年第23期14-16,共3页
Journal of Medical Forum
关键词
基底动脉尖综合征
脑梗死
磁共振成像
Top-of-the-basilar artery syndrome
Cerebral infarction
Magnetic resonance imaging
