摘要
目的探讨安理申对帕金森病后抑郁患者认知功能的作用。方法通过对本院2007-01-2011-01并发抑郁症的帕金森患者32例随机分成2组,均采取帕金森常规治疗,治疗组16例在常规治疗基础上口服安理申,对比2组治疗前、治疗8周后的汉密顿(HAMA)和简易精神状态检查(MMSE)量表的评分。结果治疗8周后治疗组的HAMD评分及MMSE评分与对照组比较差异有统计学意义(P<0.05)。结论安理申对抑郁症帕金森患者的认知功能有明显改善作用,建议临床进一步推广。
Objective To explore the effeat of aricept on cognitive function of patients with Parkinson＇s disease complicated with depression.Methods In our hospital from January 2007 to January 2011,32 depression patients with Parkinson＇s disease were randomly divided into two groups,and were given conventional treatment,the treatment group of 16 patients were given oral aricept based on the conventional treatment.HAMA,mini-mental state examination（MMSE） scores were compared in the two groups before treatment and 8 weeks later.Results After 8 weeks,MMSE and HAMD scores were significantly different in the treatment group compared with the control group（P0.05）.Conclusion Aricept can significantly improve cognitive function for Parkinson＇s disease patients with depression.
出处
《中国实用神经疾病杂志》
2012年第1期21-22,共2页
Chinese Journal of Practical Nervous Diseases
关键词
帕金森病
抑郁症状
认知功能
安理申
Parkinson＇s disease
Depression
Cognitive symptoms
Aricept
