摘要
目的观察维生素B12注射液治疗帕金森病的疗效。方法将笔者所在医院2002年1月～2012年1月收治的帕金森病患者68例分为对照组36例和治疗组32例。对照组在常规治疗的基础上给予美多巴125mg,4次/d。治疗组在对照组治疗的基础上加用维生素B12注射液6个月。两组均治疗6个月进行治疗前与治疗后帕金森症状评分量表评分,并进行比较。结果两组治疗后UPDRS评分情况为:治疗组(20.4±3.3)分,对照组(33.6±4.2)分,两组比较差异有统计学意义(P<0.05)。结论维生素B12注射液能显著缓解患者震颤、僵直、运动迟缓等症状,可明显提高患者生活质量,尤其适合最基层医疗机构的治疗,具有良好临床疗效,值得广泛推广应用。
Objective To observe the efficacy of vitamin B12 injection for the treatment of Parkinsonism.Methods 68 cases with parkinsonism from January 2002 to January 2012 in the author＇s hospital were divided into control group（36 cases） and treatment group（32 cases）.On the basis of conventional treatment,the control group were given Madopar 125 mg,4 times a day,while the treatment group received additional vitamin B12 injection for 6 months.The UPDRS goals of two groups were compared between pretreatment and 6 months after treatment.Results After the treatment,the UPDRS goals of the treatment group was（20.4±3.3）while the control group was（33.6±4.2）,there were significant difference（P 0.05）.Conclusion Vitamin B12 injection can obviously alleviate the patients＇ symptoms of tremor,rigidity,bradykinesia and improve the patients＇ life quality.It has a good effect and is worthy of promotion and application,especially suited for the primary health care sector.
出处
《中国医药科学》
2012年第22期59-60,共2页
China Medicine And Pharmacy
