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坦索罗辛在输尿管下段结石排石中的作用 被引量:1

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摘要 目的评价坦索罗辛在治疗输尿管下段结石患者中的临床疗效。方法将80例输尿管下段结石患者随机分成两组,每组40例,结石直径0.4~1.0cm。对照组口服肾石通颗粒1袋(4g),2次/d,并适量饮水和运动;治疗组在对照组治疗方案基础上予以口服盐酸坦索罗辛缓释胶囊0.4mg,每晚1次。每例患者治疗观察期不超过2周。结果 2周内,对照组排石率为42.5%(17/40),治疗组为82.5%(33/40),两组比较排石率差异有统计学意义(P<0.01)。平均排石时间对照组为8.5d,治疗组为5.2d,两组比较差异有统计学意义(P<0.05)。因发生肾绞痛而需镇痛药治疗,对照组有8例,治疗组有1例,两组均未出现明显副作用,无因不能耐受而退出者。结论坦索罗辛可明显提高输尿管下段结石排出率,减少排出时间,缓解肾绞痛发生,可作为一种有效的输尿管下段结石辅助排石治疗药物。
出处 《中国实用医药》 2011年第33期139-140,共2页 China Practical Medicine
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参考文献9

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二级参考文献27

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