信必可联合百令胶囊治疗慢性阻塞性肺疾病的临床观察被引量：15

信必可联合百令胶囊治疗慢性阻塞性肺疾病的临床观察

导出

摘要目的观察布地奈德福莫特罗吸入剂(商品名:信必可)和百令胶囊联合治疗中度以上慢性阻塞性肺疾病(COPD)稳定期患者的临床疗效。方法采用前瞻性研究方法将80例缓解期慢性阻塞性肺疾病患者随机分成对照组40例和实验组40例,治疗15周后,评价所有患者的运动耐力、血气分析与肺功能指标第一秒用力呼气量(FEV1)、第一秒用力呼气量占用力肺活量百分比(FEV1/FVC)。结果对照组与实验组上述指标均较治疗前改善(P<0.05或P<0.01),但实验组较对照组改善更为明显(P<0.05)。结论信必可联合百令胶囊治疗慢性阻塞性肺疾病疗效显著,能提高运动耐力、改善动脉血气、促进肺功能的恢复。 Objective To investigate the clinical efficacy of Symbicort in combination with Bailing capsule in moderate COPD in stable period.Methods Randomly divide 80 cases into control group and experimental group,endurance ratings,blood gas analysis and parameters of pulmonary function（FEV1,FEV1/FVC）of all patients were assessed after 15 weeks＇ treatment.Results Compared with prior treatment,all indicators above of the two group improved a lot（P0.05,P0.01）,but treatment group was even more apparent than control group（P0.05）.Conclusion Combined Symbicort and Baling capsule has a significant effect on the treatment in moderate COPD in stable period patients by enhanceing endurance ratings,improving blood gas and promoting the recovery of pulmonary function。

作者徐震黄河

机构地区新乡市中心医院呼吸内科

出处《中国实用医药》 2011年第33期39-41,共3页 China Practical Medicine

关键词慢性阻塞性肺疾病信必可百令胶囊 COPD Symbicort Balingtreasure capsule

分类号 R563.9 [医药卫生—呼吸系统]

引文网络
相关文献

参考文献3

1慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量：8252
2田德禄.中医内科学.第7版.北京:人民卫生出版社,2001:94.
3姚婉贞,常春.支气管舒张剂和吸入糖皮质激素在慢性阻塞性肺疾病中的应用[J].中华结核和呼吸杂志,2007,30(3):223-225. 被引量：99

二级参考文献27

1有创-无创序贯机械通气多中心研究协作组.以肺部感染控制窗为切换点行有创与无创序贯机械通气治疗慢性阻塞性肺疾病所致严重呼吸衰竭的随机对照研究[J].中华结核和呼吸杂志,2006,29(1):14-18. 被引量：280
2GOLD Executive Committee[DB/OL].Guidelines:Global Strategy for Diagnosis,Management,and Prevention of COPD,November 2006[2006-11-18].http://www.goldcopd.com/Guidelineitem.asp? l1 =2-12 = 1&intId =989.
3Celli BR,MacNee W,Committee members.Standard for the diagnosis and treatment of patients with COPD:a summary of the ATS/ERS position paper.Eur Respir J,2004,23:932-946.
4Celli BR,Cote CG,Marin JM,ct al.The body mass index,airflow obstruction,dyspnea and exercise capacity index in chronic obstructive pulmonary disease.N Engl J Med,2004,350:1005-1012.
5冉丕鑫王辰姚婉贞等.我国部分地区慢性阻塞性肺疾病流行病学研究[J].中华结核和呼吸杂志,2007,.
6Di Marco F, Verga M, Santus P. Effect of formoterol, tiotropium,and their combination in patients with acute exacerbation of chronic obstructive pulmonary disease: a pilot study. Respir Med,2006,100: 1925-1932.
7Turner MO, Patel A, Ginsburg S, et al. Bronchodilator delivery in acute airflow obstruction. A meta-analysis. Arch Intern Med,1997,157: 1736-1744.
8Turner MO, Gafnl A, Swan D, et al. A review and economic evaluation of bronchodilator delivery methods in hospitalized patients. Arch Intern Med, 1996,156:2113-2118.
9Levitt MA, Gambrioli EF, Fink JB. Comparative trial of continuous nebulization versus metered-dose inhaler in the treatment of acute bronchospasm. Ann Emerg Med, 1995,26:273-277.
10Gartlehner G, Hansen BA, Carson SS, et al. Efficacy and safety of inhaled corticosteroids in patients with COPD: a systematic review and meta-analysis of health outcomes. J Faro Pract, 2006,55:756.