摘要
[目的]观察痰瘀同治之通脉化浊汤对动脉粥样硬化大鼠血脂的影响。[方法]按体重将大鼠随机分为空白组、模型组、通脉化浊汤组、血脂康对照组,除空白组,其余三组建立动脉粥样硬化血脂异常模型。空白组和模型组给予等体积的生理盐水,另两组分别给予通脉化浊汤和血脂康。在干预第7、14、28天3个时点取材检测TC、TG、HDL-C、LDL-C。[结果]与模型组相比,通脉化浊汤组的TC、LDL水平均明显降低(P<0.01),HDL-C水平提高(P<0.01);与血脂康对照组比较无显著差异(P>0.05)。[结论]痰瘀同治之通脉化浊汤可降低动脉粥样硬化大鼠的血脂,可为临床运用痰瘀同治之法防治动脉粥样硬化提供实验依据。
[Objective] Phlegm of Tongmai Huazhuo Decoction of atherosclerotic blood lipid in rats.[Method]by weight The rats were randomly divided into normal group,model group,Tongmai Huazhuo soup group,Xuezhikang control group,in addition to the normal group,the other three groups established atherosclerotic dyslipidemia model.Normal group and model group were given an equal volume of saline,the other two groups were given Tongmai Huazhuo Decoction and Xuezhikang.In 7,14,28 days in the intervention first drawn three test point are based detection TC,TG,HDL-C,LDL-C.[Results] Compared with model group,Tongmai Huazhuo soup group TC,LDL levels were significantly lower（P0.01）,HDL-C levels increased（P0.01）;Xuezhikang control group with no significant difference（P0.01）.[Conclusion]Phlegm of Tongmai Huazhuo Decoction could reduce atherosclerotic rats,blood lipids,for the clinical use of the law Phlegm prevention of atherosclerosis provide experimental basis.
出处
《实用中医内科杂志》
2011年第8期31-33,共3页
Journal of Practical Traditional Chinese Internal Medicine
