摘要
目的 分析青海省布鲁杆菌病（简称布病）的流行特征及其影响因素,为制订布病防制对策提供科学依据.方法 2006- 2010年,选择青海省布病高发地区以及青海省中央补助地方公共卫生专项资金人间布病预防控制项目的5个县（河南县、达日县、天峻县、平安县、海晏县）为调查点,同时对青海省生物药品厂高危从业人员进行调查.对调查对象进行布鲁杆菌素皮内变态反应试验,同时按知情同意原则,采集血清,做虎红平板凝集试验（RBPT）和试管凝集试验（SAT）.按《全国人间布鲁氏菌病监测方案（试行）》中的调查表进行流行病学调查,询问流行病学接触史,结合临床症状和体征,按照《布鲁氏菌病诊断标准及处理原则》（GB 15988-1995）和《布鲁氏菌病诊断标准》（WS 269-2007）进行检测确诊病人.结果 在被检测的8368份血清样品中,RBPT检出阳性347份,阳性率为4.15％;SAT检测血样5346份,阳性180份,阳性率为3.37％.2009年6月对青海省生物制药厂进行跟踪调查,全厂共调查112人份,RBPT检出阳性83份,阳性率为74.11％,SAT检出阳性58份,阳性率为51.79％,确定布病新发病人8例,布病慢性期病人4例.2006 - 2010年青海省报告新发布病25例,发病高峰为每年的3-7月份,病例以牧民为主.结论 加强动物检疫,强化宣传教育、提高防护意识,可切实控制布病疫情.
Objective To analyze the epidemiological features and influencing factors of human brucellosis in Qinghai province,and to provide scientific basis for prevention and control of brucellosis.Methods From 2006 to 2010,select the high incidence areas of brucellosis in Qinghai province and five counties（Henan,Dari,Tianjun,Ping＇an and Haiyan counties） included in the “Central Subsidies to Local Public Health Special Fund Human Brucellosis Prevention and Control Projects” for the survey point,as well as high-risk employees from Qinghai Biological Pharmaceutical Factory were investigated.Combined with epidemiological questionnaire investigation [done according to the “National Human Brucellosis Surveillance Program（Trial）”],clinical symptoms and signs,confirmed human brucellosis patient were tested by intradermal allergy test,rose bengal plate agglutination test（RBPT） and standard tube agglutination test （SAT）,in accordance with “Diagnostic Criteria and Principles of Management of Brucellosis” （GB 15988-1995） and “Diagnostic Criteria for Brucellosis” （WS 269-2007）.Results Of 8368 serum samples detected,347 were RBPT positive,and the positive rate was 4.15%;5346 serum samples were tested by SAT,180 were positive,and the positive rate was 3.37%.In June 2009,112 employees in Qinghai Biological Pharmaceutical Factory were investigated on a follow-up survey,83 were RBPT positive,the positive rate was 74.11%; 58 were SAT positive,the positive rate was 51.79%.Eight of them were new cases and 4 were chronic brucellosis.Twenty five new cases were reported between 2006 and 2010.The peak incidence was from March to July.Most of the cases were herdsmen.Conclusion Strengthening animal quarantine,strengthening public education,and improving protection awareness,can effectively control the disease brucellosis.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2012年第1期88-90,共3页
Chinese Jouranl of Endemiology
