摘要
目的:观察当归拈痛汤对急性痛风性关节炎大鼠步态和关节肿胀度的影响。方法:采用向大鼠踝关节腔注射微晶型尿酸钠(MSU)混悬液方法建立急性痛风性关节炎模型,将当归拈痛汤用于模型的治疗,并与秋水仙碱做组间对照,观察造模24h后大鼠步态并进行行为学评分,并用足爪容积测量仪测定造模后不同时间大鼠的踝关节肿胀度。结果:当归拈痛汤能明显改善急性痛风性关节炎大鼠的步态异常,并能显著降低其踝关节肿胀度。结论:当归拈痛汤对急性痛风性关节炎大鼠有显著的治疗作用。
Objective：To observe the influnce of Danggui Niantong Decoction on gaits and joint swelling of rats with Acute Gouty Arthritis.Methods：Use Danggui Niantong Decoction to treat the model established by injecting monosodium urate（MSU） solution into ankle cavities of the rats,and compare with colchicine.Serum IL-1β,the gaits and joint swelling of rats in all groups were observed.Results：Danggui Niantong Decoction could siganificantly improve the gaits and inhibit joint swelling of rats with Acute Gouty Arthritis.Conclusion：The therapeutic effects of Danggui Niantong Decoction on rats with Acute Gouty Arthritis are obvious.
出处
《中华中医药学刊》
CAS
2012年第1期165-166,共2页
Chinese Archives of Traditional Chinese Medicine
基金
深圳市科技局资助项目(200903180)
