期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Ang-1在缺血性疾病中的实验研究 被引量：2

暂未订购
导出
摘要 血管生成素-1（angiopoietin-1,Ang-1）是一种促血管生长的细胞因子,在组织修复及血管发生方面起了一定作用。自Davis等于1996年发现了Ang-1,其在血管生成、发育、成熟以及维持血管稳定性等方面的重要作用受到了研究者的广泛关注。
作者 张小芳 姚宝珍 刘丹
机构地区 武汉大学人民医院儿科 武汉大学人民医院影像科
出处 《医学研究杂志》 2011年第12期143-145,共3页 Journal of Medical Research
关键词 ANG-1 缺血性疾病 实验研究 血管生成素 细胞因子 血管生长 血管发生 组织修复
分类号 R363 [医药卫生—病理学]
  • 相关文献

参考文献23

  • 1Davis S,Aldrich T H,Jones PF,etal.Iolation of angiopoietin-1 aligandf or the tie2 receptor by secretion trap expression cloning[J].Cell,1996,87(7):1161-1169.
  • 2Witzenbichler B,Westermann D,Knueppel S.Protective role of angiopoietin-1 in endotoxics hock[J].Circulation,2005,111 (1):97-105.
  • 3Cui X,Chen J,Zacharek A,et al.Nitric oxide donor up-regulation of SDFI /CXCR4 and Ang-1/Tie2 promotes neuroblast cell migration after stroke[J].J Neurosci Res,2009,87:85-92.
  • 4Suzuki Y,M on tagne K,N ishihara A,etal.BMPs promote proliferation and migration of endothelial cells via stimu lation o f VEGFA /VEGFR2 and ang iopoietin-1/Tie2 signalling[J].J Biochem,2008,143(2):199-206.
  • 5Daly C,Pasnikowski E,Burova E,etal.Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells[J].Proc Natl Acad Sci USA,2006,103 (42):15491-15496.
  • 6Papapetropolous A,Garcia-Cardena G,Dengler TJ,etal.Direct actions of angiopoietin-1 on human endothelium:evidence for network stabilization,cell survival,and interaction with other angiogenic growth factors[J].Lab Invest,1999,72:213-223.
  • 7Chen JX,Stinnett A.Disruption of Ang-1 /Tie-2 signaling contributes to the impaired myocardial vascular maturation and angiogenesis in type Ⅱ diabetic mice[J].Arterioscler Thromb Vasc Biol,2008;28:1606.
  • 8Huang J,Inoue M,Hasegawa M,et al.Sendai viral vector mediated angiopoietin-1 gene transfer for experimental ischemic limbdisease[J].Angiogenesis,2009,26(4):532-539.
  • 9Benest AV,Salmon AH,Wang W,et al.VEGF and angiopoietin-1 stimulate different angiogenic phenotypes that combine to enhance functional neovascularization in adult tissue[J].Microcirculation,2006,13:419-428.
  • 10Liu X,Chen Y,Zhang F,et al.Synergistically therapeutic effects of VEGF and angiopoietin-1 on ischemic rat myocardium[J].ScandCardio vasc J,2007,41:95.

二级参考文献22

  • 1王伟,张志坚,林建华3,吴秀丽,余良宏,康德智.大鼠骨髓间质干细胞培养扩增及表面标志[J].福建医科大学学报,2005,39(1):5-8. 被引量：16
  • 2孙丽杰,崔鸣,冯新恒,王佐岩,马康涛,毛节明,沈丽,陈凤荣,周春燕.血管生成素1基因上调Tie2受体表达促进大鼠急性心肌梗死血管生成的实验研究[J].中国介入心脏病学杂志,2005,13(1):41-44. 被引量：5
  • 3Xu HX, Li GS, Jiang H, et al. Implantation of BM cells transfected with phVEGF165 enhances functional improvement of the in farcted heart. Cytotherapy, 2004,6(3):204-211.
  • 4Hurtado PA, Wang X, SipooI, et al. Viral and nonviral factors causing nonspecific replication of tumor- and tissue specific promoter-dependent oncolytic adenoviruses. Mol Ther, 2005,11 (4) ; 563-577.
  • 5Santos RA, Frezard F, Ferreira AJ. Angiotensin-(1-7): blood, heart, and blood vessels, Curr Med Chem Cardiovasc Hematol Agents, 2005,3(4):383-391.
  • 6Takemura G, Fujiwara H. Role of apoptosis in remodeling after myocardial infarction. Pharmaeol Ther, 2004, 104(1) :1-16.
  • 7Cho CH, Sung HK, Kim KT, et al. COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangio genesis, and blood flow in a diabetic mouse model. Proc Natl Acad Sci USA, 2006,103(13) :4946-4951.
  • 8Vannan M, McCreery T, Li P, et al. Ultrasound mediated trans fection of canine myocardium by intravenous administration of cat ionic microbubble-linked plasmid DNA. J Am Soc Eehocardiogr 2002,15(3) :214-218.
  • 9Ferrari R, Guardigli G, Mele D, et al. Oxidative stress during myocardial ischaemia and heart failure[ J]. Curr Pharm Des, 2004, 10(14) :1699 - 1711.
  • 10Tsutsui H, Ide T, Kinugawa S. Mitochondrial oxidative stress, DNA damage, and heart failure[ J ]. Antioxid Redox Signal, 2006, 8(9 - 10) :1737 - 1744.

共引文献10

同被引文献18

  • 1贺石林．中医科研设计与统计学[M].长沙：湖南科学技术出版社，2003．38．
  • 2易忠盛 何明菊.浅谈中药汤剂的煎煮.四川中医,1992,(8):27-27.
  • 3姚杰良,王仁荣,陈宏伟.量化煎服中药 疗效事半功倍[J].陕西中医,2007,28(6):735-736. 被引量：3
  • 4Chen S, Guo L, et al. Association of serum angiopoietin-1, an- giopoietin-2 and angiopoietin-2 to angiopoietin-I ratio with heart failure in patients with acute myocardial infarction [J]. Exp Ther Med,2013,5(3) :937-941.
  • 5Paul A, Nayan. Angiopoietin-1 expressing adipose stem cells genetically modified with baculovirus nanocomplex: investi- gation in rat heart with acute infarction[J]. Int J Nanomedicin- em, 2012,7 : 663-682.
  • 6Huang H,Lai JY. Specifically targeting angiopoietin-2 in- hibits angiogenesis, Tie2-expressing monocyte infiltration, and tumor growth [J]. Clin Cancer Res,2011,17 (5) : 1001 - 1008.
  • 7Helisch A,Schaper W.Arteriogenesis:the development and growth of collateral arteries[J].Microcirculation,2003;10(1):83-97.
  • 8Iribarrenl C,Phelps BH,Darbinian JA,et al.Circulating angiopoietins-1and-2,angio-poietin receptor Tie-2 and vascular endothelial growth factorA as biomarkers of acute myocardial infarction:a prospective nested casecontrol study[J].BMC Cardiovasc Disord,2011;11(31):1-9.
  • 9Lee KW,Md GYH,Blann AD.Plasma angiopoietin-1,angiopoietin-2,angio-poietin receptor Tie-2,and vascular endothelial growth factor levels in acute coronary syndromes[J].Circulation,2004;110:2355-60.
  • 10Link A,Pss J,Rbah R,et al.Circulating angiopoietins and cardiovascular mortality in cardiogenic shock[J].Eur Heart J,2013;34(22):1551-62.

引证文献2

二级引证文献17

医学研究杂志
2011年 第12期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部