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神经病理性疼痛与电压门控性钠离子通道机制研究的新进展

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摘要 神经病理性疼痛是一种主要由外周或中枢神经感染、创伤、压迫、代谢障碍引起的难治性疼痛[1]。近来诸多学者研究发现在神经病理性疼痛的病理状态下,可能与钠离子、钙离子、钾离子等电压门控离子通道、受体、各种神经肽、酶、
出处 《医药论坛杂志》 2011年第21期201-203,共3页 Journal of Medical Forum
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  • 1ColomboB,Annovazzi P O, Comi G. Medicationa for neu- ropathic pain currcnt trends [ J ]. Ncurol Sci, 2006,27 (Suppl 2) :S183-S189.
  • 2Tarnawal, Bolcskei H, Kocsis P. Blockers of voltage - gated eodium channela for the treatment of central nerv- ous system discascs[ J]. Rccent Pat CNS Drug Discov, 2007,2:57-78.
  • 3王英伟,卞金俊,邓小明,郭超.神经病理性疼痛大鼠背根神经节钠离子通道β亚基mRNA表达的变化[J].中华麻醉学杂志,2006,26(6):555-557. 被引量:8
  • 4Ekberg J, Adama DJ. Neuronal voltage gated sodium channel subtypes, key roles in inflammatory and neuro- pathicpain, Int J [ J ]. Biochem Cell Biol, 2006,38 : 2005- 2010.
  • 5Xiao H S. Huang Q H. Zhang F X, et al. Identification of gene expression profile of dorsal root ganglion in the ratperiheral axotomy model of neuropathic pain[ J]. Pro Natl Acad Sei U S A, 2002,99:8360-8365.
  • 6Zhao P,Waxman SG, Hoins BC. Sodiun channel expres- sion in the ventral posterolateral nucleus of the thalamus after peipberal nerve injury[ J]. Mol Pain,2006,2:27.
  • 7Hains BC, Soab CY, Waxman SG. Alterations in burst firing of thalamic VPL neurona and reversal by Na ( v ) 1.3 antisensc afterspinal cord injury [ J]. J Neurophysi- ol, 2006,95 : 3343 -3352.
  • 8DjoubriL, Newton R, Levinaon S R, et al. Sensory and electrophysiological properties of guinea - pig senaory neurona expressring Navl. 7 (PNI) Na + channel alpha aubunit protein[ J]. J Physiol,2003 ,546 :565-576.
  • 9Raymond C K, Castle J, Garrett - EngeleP, et al. Expres- sion of alternatively spliced sodium channel alpha - sub- unit genes, Unique aplicing patterns are obscerved in dornal root ganglia[ J ]. J Riol Chem, 2004,279:46234- 46241.
  • 10Nassar M A, Stiriling L C, Forlanl G, et al . Nocicep- torapecflic gene deletion reveals a major rol for Navl. 7 (PNI) in acute and inflammatory pain [ J ]. Proe Natl Acad Aci USA ,2004,10 : 12706-12711.

二级参考文献37

  • 1Dray A, Future pharmacologic management of neuropathic pain [J]. Orofac Pain, 2004, 18(4): 381-385
  • 2Dworkin RH., Backonja M., Rowbotham MC, et al. Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations[J]. Arch Neurol, 2003, 60(11): 1524-1534
  • 3Meunier A., Braz J, Cesselin F, et al. From inflammation to pain: experimental gene therapy[J]. Med Sci (Paris), 2004, 20(3): 325-330
  • 4Pohl M, Braz J. Gene therapy of pain: emerging strategies and future directions[J]. Eur J Pharmacol, 2001, 429(1-3): 39-48
  • 5Pohl M, Meunier A, Hamon M, et al. Gene therapy of chronic pain [J]. Curr Gene Ther, 2003, 3(3): 223-238
  • 6Glorioso JC, Mata M, Fink DJ. Gene therapy for chronic pain [J]. Curr Opin Mol Ther, 2003, 5(5): 483-488
  • 7Chuang YC, Chou AK, Wu PC, et al. Gene therapy for bladder pain with gene gun particle encoding pro-opiomelanocortin cDNA [J]. J Urol, 2003, 170(5):2044-2048
  • 8Chuang YC, Yang LC, Chiang PH, et al. Gene gun particle encoding preproenkephalin cDNA produces analgesia against capsaicininduced bladder pain in rats[J]. Urology, 2005, 65(4): 804-810
  • 9Reilly JP, Grise MA, Fortuin FD, et al. Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients [J]. J Interven Cardiol, 2005, 18 (1): 27 -31.
  • 10Gudmundsson G, Bosch A, Davidson BL, et al. Interleukin-10 modulates the severity of hypersensitivity pneumonitis in mice [J]. Am J Respir Cell Mol Biol, 1998, 19(5): 812-818

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