摘要
德国小蠊在医学与经济方面的重要性和危害性促使人们对其进行广泛的化学防治,但随之产生严重的抗性。该文以德国小蠊钠离子通道抗性即击倒抗性(knockdown resistance,kdr)为主题,重点论述了德国小蠊kdr抗性的发现历史、分子与进化机制,扼要介绍了钠离子通道结构特征、kdr突变的功能研究方法以及近期所取得的代表性研究结果。此外,概述了该领域的最新研究方向及结果对德国小蠊防制、抗性监测与治理等的理论与指导意义。
Wide application of insecticides has resulted in severe resistance in the German cockroach （Blattella germanica）. This study reviews the discovery and molecular and evolutional mechanisms of the knockdown resistance （kdr）, also known as the sodium channel resistance, with emphasis on the molecular structure, functional research methods of kdr mutations and up-to- date representative results. In addition, the latest findings are summarized to inform the prevention, control and resistance monitoring of the cockroaches.
出处
《中国媒介生物学及控制杂志》
CAS
CSCD
2011年第6期611-614,共4页
Chinese Journal of Vector Biology and Control
关键词
德国小蠊
击倒抗性
钠离子通道
点突变
Blattella germanica
Sodium channel
Knockdown resistance
Point mutation
