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耐药突变选择窗理论的研究与意义

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摘要 随着抗菌药的广泛应用，细菌的耐药性问题变得越来越严重。现在几乎每一种有效的抗菌药物都发现了相应的耐药菌，其耐药水平越来越高，甚至出现了多重耐药菌株。传统的基于最小抑菌浓度（MIC）的治疗策略是通过抗菌药物杀死或抑制敏感细菌而控制感染，再通过宿主防御系统清除耐药变异菌。
作者 李虹 叶云 王国俊
机构地区 泸州医学院药学院
出处 《泸州医学院学报》 2011年第6期758-761,共4页 Journal of Luzhou Medical College
关键词 耐药突变选择窗 多重耐药菌株 抗菌药物 最小抑菌浓度 宿主防御系统 敏感细菌 耐药水平 控制感染
分类号 R96 [医药卫生—药理学]
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参考文献18

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泸州医学院学报
2011年 第6期

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