摘要
目的探讨动脉硬化相关指标与亚临床甲状腺功能减退的关系及其意义。方法将2008年1月至2010年1月在我院住院或门诊就诊的45例亚临床甲状腺功能减退患者作为观察组,同时选取50例健康体检志愿者作为对照组,分别测定并比较两组研究对象的甲状腺功能、血脂、血尿酸、纤维蛋白原及颈动脉内膜中层厚度。结果亚临床甲状腺功能减退患者血脂、血尿酸及纤维蛋白原均明显高于健康对照组,其颈动脉中膜内层增厚程度也较对照组显著,差异均有统计学意义(P<0.05)。结论亚临床甲状腺功能减低是甲状腺功能减低的前期阶段,患者血清血脂、血尿酸及纤维蛋白原等动脉硬化危险因素显著升高,应采取适当的干预措施或定期随访是有必要的。
Objective to study the atherosclerosis related indicators and subclinical hypothyroidism relationship and its significance.Methods from January 2008 in January 2010 in our hospital outpatient clinic of hospitalization or 45 cases subclinical hypothyroidism patients as research group and also select 50 cases of healthy check-up volunteers as control group,were determined and compared between the two groups of object of study thyroid function,blood fat and blood uric acid,fibrinogen and carotid intima-media thickness.Results the clinical hypothyroidism patient blood fat and blood uric acid and fibrinogen were significantly higher in healthy controls,the carotid artery thickening in the inner membrane was significantly,a level are statistically significant difference（P0.05）.Conclusion the clinical thyroid function reduce is reducing the thyroid function in patients with early stage,blood fat and blood serum uric acid and fibrinogen atherosclerosis risk factors such as significantly increased,should adopt appropriate intervention measures or regular follow-up is necessary.
出处
《中国实验诊断学》
北大核心
2011年第12期2046-2048,共3页
Chinese Journal of Laboratory Diagnosis
