摘要
目的 观察术前选择性动脉灌注化疗加栓塞对中晚期直肠癌的近期治疗效果。方法 选择 6 3例经活检证实的中晚期直肠癌患者 ,经直肠上动脉或双侧髂内动脉造影确定肿瘤的主要供血动脉 ,向内注入 40 %碘化油及化疗药物混合的乳剂 ,其它靶血管内注入化疗药物 ( 5 Fu +MMC +DDP) ,治疗后观察患者肠出血、脓血便、肛门下坠、肠梗阻等症状的缓解情况及术中肿瘤的游离难易度、创面出血情况。结果 治疗后患者肠出血、脓血便、肛门下坠及不全性肠梗阻症状得到明显缓解 ,术中肿瘤与周围组织间隙明显、利于游离 ,创面出血少。结论 术前行选择性动脉灌注化疗加栓塞可改善中晚期直肠癌患者的临床症状 ,提高切除率 ,可能对直肠癌根治术后肿瘤的复发和肝转移有预防作用。
? Objective To evaluate the short term curative effects of preoperative selective intraarterial embolism and regional chemotherapy on advanced rectal cancer.Methods 63 cases were treated by selective arterial angiography in internal iliac artery and superior rectal artery in order to find the main artery of cancer, which was injected with 40% iodinated oil mixed with chemotherapy drugs.The signs such as major colonic bleeding,hematochezia mixed with pus,intestinal obstruction were observed after treatment.Results The clinical signs were remitted.Tumor tissue was easier to be seperated from adjacent normal tissue with less bleeding.Conclusions The preoperative selective intraarterial embolism plus regional chemotherapy can remit the clinical symptoms of advanced rectal cancer,increase the rate of radical resection,and avoid recurrence and hepatic metastasis. 〔
出处
《中国肿瘤临床与康复》
2000年第1期91-92,共2页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
直肠肿瘤
区域化疗
化学栓塞
效果
rectal neoplasms
regional chemotherapy
chemoembolism
effects
